SCHEMBL15826552

SCHEMBL15826552

CC(C)c1cccc(C(C)C)c1N1[C]N(c2c(C(C)C)cccc2C(C)C)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.43
MGLL Q99685 1/20 0.43
DPP4 P27487 5/20 0.40
GABRA1 P14867 3/20 0.40
GABRB2 P47870 2/20 0.40
TSHR P16473 2/20 0.40
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
LMNA P02545 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
HPGD P15428 1/20 0.40
GABRB1 P18505 1/20 0.40
PTGS1 P23219 1/20 0.40
SLC6A2 P23975 1/20 0.40
HTR2C P28335 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15826551 1.00 FAAH (0.43) FAAHMGLLDPP4GABRA1GABRB2
SCHEMBL15826554 0.72 FAAH (0.43) FAAHMGLLDPP4GABRA1GABRB2
SCHEMBL30265954 0.72 FAAH (0.43) FAAHMGLLDPP4GABRA1GABRB2
SCHEMBL222225 0.71 GABRA1 (0.43) FAAHMGLLDPP4GABRA1GABRB2
SCHEMBL28152643 0.71 DPP4 (0.46) FAAHMGLLDPP4GABRA1GABRB2
SCHEMBL220287 0.69 GABRA1 (0.41) FAAHDPP4GABRA1GABRB2TSHR
SCHEMBL20408268 0.68 HTR7 (0.43) FAAHMGLLDPP4NR1H2NR1H3
SCHEMBL16946344 0.67 FAAH (0.42) FAAHMGLLDPP4GABRA1GABRB2
SCHEMBL2523156 0.67 DPP4 (0.38) FAAHDPP4GABRA1GABRB2TSHR
SCHEMBL456981 0.67 GABRA1 (0.43) FAAHMGLLDPP4GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469715-B2 Method for producing formaldehyde/CO2 copolymers COVESTRO DEUTSCHLAND AG (DE) 2016-10-18 US disclosed
US-20150337070-A1 METHOD FOR PRODUCING FORMALDEHYDE/CO2 COPOLYMERS BAYER MATERIALSCIENCE AG (DE) 2015-11-26 US disclosed
EP-2938651-A2 METHOD FOR PRODUCING FORMALDEHYDE/CO2 COPOLYMERS Covestro Deutschland AG (DE) 2015-11-04 EP disclosed
WO-2014095861-A2 METHOD FOR PRODUCING FORMALDEHYDE/CO2 COPOLYMERS BAYER MATERIALSCIENCE AG (DE) 2014-06-26 WO disclosed