Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.33 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14725535 | 1.00 | ALDH1A1 (0.38) | ALDH1A1LMNAPOLBGAAMAPK1 | |
| SCHEMBL16299766 | 1.00 | ALDH1A1 (0.38) | ALDH1A1LMNAPOLBGAAMAPK1 | |
| SCHEMBL19772808 | 0.89 | PTPN1 (0.39) | ALDH1A1POLBMAPK1PTPN1MEN1 | |
| SCHEMBL16299814 | 0.89 | USP2 (0.42) | ALDH1A1POLBMAPK1PTPN1MEN1 | |
| SCHEMBL2621420 | 0.86 | LMNA (0.47) | ALDH1A1LMNAPOLBGAAMAPK1 | |
| SCHEMBL26167583 | 0.86 | LMNA (0.47) | ALDH1A1LMNAPOLBGAAMAPK1 | |
| SCHEMBL9604620 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNAPOLBGAAMAPK1 | |
| SCHEMBL15829780 | 0.85 | ALDH1A1 (0.41) | ALDH1A1LMNAPOLBGAAMAPK1 | |
| SCHEMBL14978164 | 0.83 | PTPN1 (0.44) | POLBMAPK1PTPN1MEN1USP2 | |
| SCHEMBL20730008 | 0.83 | PTPN1 (0.44) | POLBMAPK1PTPN1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9814777-B2 | Targeting lipids | ARBUTUS BIOPHARMA CORPORATION (CA) | 2017-11-14 | — | — | US | disclosed |
| US-20160375137-A9 | TARGETING LIPIDS | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2016-12-29 | — | — | US | disclosed |
| US-20140179761-A1 | TARGETING LIPIDS | TEKMIRA PHARMACEUTICALS CORPORATION (CA) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179761-A1 | TARGETING LIPIDS | LY96, ABHD10, APOB | ALDH1A1 1600/4885LMNA 169/4885POLB 450/4885 |
| US-20160375137-A9 | TARGETING LIPIDS | LY96, ABHD10, APOB | ALDH1A1 1600/4885LMNA 169/4885POLB 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.