Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | APP | P05067 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | AKT1 | P31749 | 1/20 | 0.57 |
| ▸ | F7 | P08709 | 1/20 | 0.57 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.57 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.57 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951025 | 0.82 | ALDH1A1 (0.61) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL27356346 | 0.82 | ALDH1A1 (0.61) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL2323169 | 0.82 | ALDH1A1 (0.61) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL7365569 | 0.81 | KMO (0.67) | ALDH1A1CYP1A1CYP1A2CYP1B1CYP3A4 | |
| SCHEMBL27494751 | 0.81 | CYP1A1 (0.63) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Bromide SCHEMBL4269509 | 0.80 | ALDH1A1 (0.59) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Pyridine SCHEMBL27582270 | 0.80 | AKT1 (0.76) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL27766059 | 0.80 | F7 (0.62) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL9488231 | 0.79 | PLOD2 (0.59) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL10036802 | 0.78 | CYP1A1 (0.65) | ALDH1A1APPGAAHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118598851-A | 5-Aminoindole chalcone compound and preparation method and application thereof | 平顶山学院 | 2024-09-06 | — | — | CN | claimed |
| WO-2023066190-A1 | COMPOUNDS AND THEIR USES AS GPR183 INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-04-27 | — | — | WO | claimed |
| CN-110938845-A | Plating solution for electrolytic tinning | 上村工业株式会社 | 2020-03-31 | — | — | CN | claimed |
| CN-108892859-A | A kind of antibacterial song Shandong card | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 2018-11-27 | — | — | CN | claimed |
| WO-2012145069-A2 | MATERIALS AND METHODS USEFUL TO INDUCE CELL DEATH VIA METHUOSIS | THE UNIVERSITY OF TOLEDO (US) | 2012-10-26 | — | — | WO | claimed |
| CN-114507215-B | Compound serving as PAK4 kinase inhibitor and preparation method and application thereof | 成都海博为药业有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-118598851-A | 5-Aminoindole chalcone compound and preparation method and application thereof | 平顶山学院 | 2024-09-06 | — | — | CN | disclosed |
| CN-114507215-A | Compound serving as PAK4 kinase inhibitor and preparation method and application thereof | 成都海博为药业有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114502555-A | Derivatives of 4- (imidazo [1,2-a ] pyridin-3-yl) -N- (pyridin-3-yl) pyrimidin-2-amines for the treatment of proliferative diseases and disorders | 常州千红生化制药股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114269742-A | Derivatives of 4- (imidazo [1,2-a ] pyridin-3-yl) -N- (pyridinyl) pyrimidin-2-amines as therapeutic agents | 常州千红生化制药股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-108892859-A | A kind of antibacterial song Shandong card | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 2018-11-27 | — | — | CN | disclosed |
| CN-108888316-A | A kind of antimicrobial form song Shandong card | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | 2018-11-27 | — | — | CN | disclosed |
| US-20030149065-A1 | ARYLKYLAMINE SPIROFUROPYRIDINES USEFUL IN THERAPY | ASTRAZENECA AB (SE) | 2003-08-07 | — | — | US | disclosed |
| EP-1147114-B1 | NOVEL ARALKYL AMINES OF SPIROFUROPYRIDINES USEFUL IN THERAPY | ASTRAZENECA AB (SE) | 2003-05-21 | — | — | EP | disclosed |
| CN-1337964-A | Novel spirofuropyridine aralkylamines useful in therapy | ASTRAZENECA AB (SE) | 2002-02-27 | — | — | CN | disclosed |
| EP-0989973-A1 | CHALCONES HAVING ANTIPROLIFERATIVE ACTIVITY | INDENA S.p.A. (IT) | 2000-04-05 | — | — | EP | disclosed |
| WO-1998058913-A1 | CHALCONES HAVING ANTIPROLIFERATIVE ACTIVITY | INDENA S.P.A. (IT) | 1998-12-30 | — | — | WO | disclosed |
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |
| US-5011847-A | 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO., INC. (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0402156-A1 | New 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149065-A1 | ARYLKYLAMINE SPIROFUROPYRIDINES USEFUL IN THERAPY | CBR1, CBR3, NR3C2 | ALDH1A1 426/4885APP 3542/4885GAA 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.