Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23925146 | 0.81 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1TP53POLBTDP1 | |
| SCHEMBL26111986 | 0.78 | SMN1; SMN2 (0.59) | L3MBTL1ALDH1A1TP53POLBTDP1 | |
| SCHEMBL9971825 | 0.78 | PARP1 (0.49) | L3MBTL1ALDH1A1POLBTDP1SCN9A | |
| SCHEMBL23925097 | 0.78 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1TP53POLBTDP1 | |
| SCHEMBL30202774 | 0.77 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1TP53KMT2AMEN1 | |
| SCHEMBL31669103 | 0.72 | TP53 (0.42) | ALDH1A1TP53KMT2AMEN1GAA | |
| SCHEMBL20139976 | 0.70 | JAK2 (0.42) | — | |
| SCHEMBL92518 | 0.69 | L3MBTL1 (0.56) | L3MBTL1KMT2AMEN1RAB9AGAA | |
| SCHEMBL2038709 | 0.68 | TSHR (0.52) | L3MBTL1POLBTDP1KMT2AMEN1 | |
| SCHEMBL124189 | 0.68 | SMN1; SMN2 (0.49) | ALDH1A1TP53POLBRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |