Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23925097 | 0.81 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1POLBTDP1TP53 | |
| SCHEMBL1583701 | 0.81 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1POLBTDP1TP53 | |
| SCHEMBL30202774 | 0.80 | L3MBTL1 (0.64) | L3MBTL1ALDH1A1TP53KMT2ARAB9A | |
| SCHEMBL829466 | 0.76 | SMN1; SMN2 (0.65) | L3MBTL1ALDH1A1POLBTDP1TP53 | |
| SCHEMBL829196 | 0.75 | SMN1; SMN2 (0.63) | L3MBTL1ALDH1A1POLBTDP1TP53 | |
| SCHEMBL29223607 | 0.73 | SMN1; SMN2 (0.45) | L3MBTL1ALDH1A1POLBTDP1KMT2A | |
| SCHEMBL21089037 | 0.73 | TP53 (0.51) | ALDH1A1POLBTDP1TP53RAB9A | |
| SCHEMBL92518 | 0.71 | L3MBTL1 (0.56) | L3MBTL1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL21089079 | 0.71 | TP53 (0.45) | ALDH1A1POLBTDP1TP53KMT2A | |
| SCHEMBL23064553 | 0.70 | TP53 (0.45) | L3MBTL1ALDH1A1TP53KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4136084-A1 | BCL-2 INHIBITOR | BeiGene, Ltd. (KY) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021208963-A1 | BCL-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-10-21 | — | — | WO | disclosed |