Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2106013 | 0.82 | CYP1A2 (0.53) | FAAHTRPV1MGLLCYP1A2 | |
| SCHEMBL23925146 | 0.80 | L3MBTL1 (0.49) | L3MBTL1GAAKMT2AMEN1RAB9A | |
| SCHEMBL2583030 | 0.79 | GAA (0.61) | GAAKMT2AMEN1RAB9AMGLL | |
| SCHEMBL92518 | 0.78 | L3MBTL1 (0.56) | L3MBTL1GAAKMT2AMEN1RAB9A | |
| SCHEMBL22635853 | 0.78 | L3MBTL1 (0.47) | L3MBTL1GAAKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23925097 | 0.77 | L3MBTL1 (0.46) | L3MBTL1GAAKMT2AMEN1RAB9A | |
| SCHEMBL1583701 | 0.77 | L3MBTL1 (0.46) | L3MBTL1GAAKMT2AMEN1RAB9A | |
| SCHEMBL22635874 | 0.77 | L3MBTL1 (0.46) | L3MBTL1GAAKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL22724801 | 0.76 | TRPV1 (0.59) | GAAFAAHTRPV1KMT2AMEN1 | |
| SCHEMBL10883109 | 0.76 | SIGMAR1 (0.62) | L3MBTL1KMT2AMEN1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023022497-A1 | SOS1 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-02-23 | — | — | WO | disclosed |