Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 3/20 | 0.39 |
| ▸ | FNTB | P49356 | 3/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840410 | 0.84 | GLO1 (0.35) | — | |
| SCHEMBL15840416 | 0.84 | BMP1 (0.43) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17323294 | 0.84 | CTSS (0.37) | CTSSCTSK | |
| SCHEMBL22873096 | 0.83 | CA12 (0.41) | TSHRFNTAFNTBPGGT1BMEN1 | |
| SCHEMBL17323373 | 0.82 | NMT2 (0.36) | — | |
| SCHEMBL15840383 | 0.82 | PTGS1 (0.39) | — | |
| SCHEMBL15840384 | 0.81 | SIRT6 (0.41) | CTSSCTSK | |
| SCHEMBL15840414 | 0.81 | GLO1 (0.44) | — | |
| SCHEMBL15840455 | 0.80 | NMT1 (0.36) | — | |
| SCHEMBL22297882 | 0.80 | SIRT6 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015185467-A1 | PEPTIDES AS OXYTOCIN AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-12-10 | — | — | WO | disclosed |
| WO-2014095773-A1 | PEPTIDES AS OXYTOCIN AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-06-26 | — | — | WO | disclosed |