Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 4/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1584775 | 0.76 | ALDH1A1 (0.51) | MEN1KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL4098207 | 0.76 | MEN1 (0.53) | MEN1KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL4164688 | 0.76 | ALDH1A1 (0.51) | MEN1KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL3518684 | 0.75 | GRIK1 (0.46) | — | |
| SCHEMBL11315740 | 0.75 | HPGD (0.50) | MEN1KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL15978138 | 0.75 | FPR1 (0.51) | CFTRMEN1KMT2AHPGDKDM4E | |
| Hydrogen Sulfide SCHEMBL27583639 | 0.75 | HPGD (0.50) | MEN1KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL7521745 | 0.73 | ALDH1A1 (0.48) | MEN1KMT2AHPGDKDM4EALDH1A1 | |
| SCHEMBL3993882 | 0.73 | KDM4E (0.48) | HPGDKDM4EALDH1A1SMN1; SMN2PGR | |
| SCHEMBL27422649 | 0.73 | ALDH1A1 (0.49) | KMT2AHPGDKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006070292-A2 | PYRIMIDINE COMPOUNDS AS ANTI-ICTOGENIC AND/OR ANTI-EPILEPTOGENIC AGENTS | QUEEN'S UNIVERSITY AT KINGSTON (US) | 2006-07-06 | — | — | WO | disclosed |