Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16560329 | 0.79 | CCR1 (0.40) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL15409988 | 0.79 | KDM4E (0.37) | KDM4EALDH1A1 | |
| SCHEMBL16166585 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL22122693 | 0.78 | KDM4E (0.36) | KDM4EALDH1A1ADRA2AADRA2BADRA2C | |
| SCHEMBL13878887 | 0.78 | HTR2C (0.37) | KDM4EALDH1A1MBOAT4 | |
| SCHEMBL27934647 | 0.75 | KDM4E (0.37) | KDM4EALDH1A1 | |
| SCHEMBL14948664 | 0.75 | HRH3 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL14552974 | 0.75 | GBA1 (0.41) | GBA1KDM4EALDH1A1ADRA2AADRA2B | |
| SCHEMBL15410730 | 0.74 | S1PR1 (0.34) | KDM4EALDH1A1 | |
| SCHEMBL14471375 | 0.74 | MBOAT4 (0.37) | KDM4EALDH1A1MBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002475-A1 | PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS | EPICS THERAPEUTICS (BE) | 2025-01-02 | — | — | US | disclosed |
| US-12091400-B2 | Piperidine derivatives as METTL3 inhibitors | EPICS THERAPEUTICS (BE) | 2024-09-17 | — | — | US | disclosed |
| US-20240270716-A1 | PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS | EPICS THERAPEUTICS (BE) | 2024-08-15 | — | — | US | disclosed |
| EP-2940024-B1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2018-12-05 | — | — | EP | disclosed |
| US-9416144-B2 | Benzoxazine oxazolidinone compound, preparation method and application thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2016-08-16 | — | — | US | disclosed |
| US-9416144-B2 | Benzoxazine oxazolidinone compound, preparation method and application thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2016-08-16 | — | — | US | disclosed |
| US-9416144-B2 | Benzoxazine oxazolidinone compound, preparation method and application thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2016-08-16 | — | — | US | disclosed |
| US-20150336984-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2015-11-26 | — | — | US | disclosed |
| US-20150336984-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2015-11-26 | — | — | US | disclosed |
| US-20150336984-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2015-11-26 | — | — | US | disclosed |
| EP-2940024-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2015-11-04 | — | — | EP | disclosed |
| EP-2940024-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2015-11-04 | — | — | EP | disclosed |
| WO-2014101765-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | 中国科学院上海药物研究所 (CN) | 2014-07-03 | — | — | WO | disclosed |
| CN-103896963-A | Benzoxazine oxazolidinone compounds, preparation method and applications thereof | SHANGHAI INST MATERIA MEDICA | 2014-07-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270716-A1 | PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS | METTL3, METTL16, DIMT1 | GBA1 3392/4885KDM4E 872/4885ALDH1A1 205/4885 |
| US-20250002475-A1 | PIPERIDINE DERIVATIVES AS METTL3 INHIBITORS | METTL3, METTL16, DIMT1 | GBA1 3392/4885KDM4E 872/4885ALDH1A1 205/4885 |
| US-20150336984-A1 | BENZOXAZINE OXAZOLIDINONE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | OXA1L, XDH, MYD88 | GBA1 384/4885KDM4E 3712/4885ALDH1A1 818/4885 |
| US-12091400-B2 | Piperidine derivatives as METTL3 inhibitors | METTL3, METTL16, DIMT1 | GBA1 3392/4885KDM4E 872/4885ALDH1A1 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.