SCHEMBL15856498

SCHEMBL15856498

Cc1cc(C#N)cc(-c2cccc3ccccc23)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 3/20 0.47
MCL1 Q07820 2/20 0.46
XDH P47989 2/20 0.42
SLC22A12 Q96S37 1/20 0.42
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
STK10 O94804 1/20 0.40
SLK Q9H2G2 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
PIM1 P11309 1/20 0.39
ACMSD Q8TDX5 1/20 0.39
ENPP3 O14638 1/20 0.39
ENPP1 P22413 1/20 0.39
ALOX15 P16050 3/20 0.39
KDM4E B2RXH2 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30545233 0.83 ENPP3 (0.47) MCL1CA1CA2MAOAMAOB
SCHEMBL838870 0.83 ENPP3 (0.47) MCL1CA1CA2MAOAMAOB
SCHEMBL10051153 0.83 MCL1 (0.47) MCL1XDHSLC22A12CA1CA2
Phosphine SCHEMBL28240948 0.81 ENPP3 (0.46) MCL1CA1CA2MAOAMAOB
SCHEMBL15853155 0.81 MCL1 (0.43) MCL1XDHSLC22A12CA1CA2
SCHEMBL15853175 0.80 ADRA2C (0.54) MCL1CA1CA2STK10SLK
SCHEMBL5967725 0.79 PGR (0.48) GRM5XDHMAOAMAOBPIM1
SCHEMBL6278115 0.78 MCL1 (0.43) GRM5MCL1XDHSLC22A12CA1
SCHEMBL27454841 0.77 CA12 (0.45) MCL1CA1CA2MAOAMAOB
SCHEMBL26754072 0.77 PIM1 (0.53) MCL1XDHSLC22A12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140183468-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-03 US disclosed