Sulfuric Acid

Sulfuric Acid

SCHEMBL158676

ClCN1CCc2ccccc2CC1.O=S(=O)(O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.49
LMNA P02545 1/20 0.49
THRB P10828 1/20 0.49
TSHR P16473 1/20 0.49
PMP22 Q01453 1/20 0.49
HDAC1 Q13547 2/20 0.45
HDAC6 Q9UBN7 1/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
HTR7 P34969 3/20 0.43
HDAC3 O15379 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
HPGD P15428 1/20 0.42
CYP2C19 P33261 1/20 0.42
HTR1A P08908 1/20 0.42
DRD2 P14416 1/20 0.42
HTR2A P28223 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158570 0.93 HDAC1 (0.47) HSD17B10LMNATHRBTSHRPMP22
SCHEMBL162670 0.88 MAOA (0.46) HDAC1HDAC6MEN1KMT2AHTR7
Bromide SCHEMBL161201 0.86 MAOA (0.45) HDAC1HDAC6HTR7DRD2DRD3
Phosphoric Acid SCHEMBL166017 0.85 HDAC1 (0.49) HDAC1HDAC6MEN1KMT2AHTR7
Malonic Acid SCHEMBL160931 0.82 HDAC1 (0.50) TSHRHDAC1HDAC6MEN1KMT2A
Glycolic Acid SCHEMBL162066 0.82 HDAC1 (0.47) HDAC1HDAC6MEN1KMT2AHTR7
Nitric Acid SCHEMBL163518 0.82 HDAC1 (0.43) HDAC1HDAC6MEN1KMT2AHTR7
Maleic Acid SCHEMBL161823 0.81 MEN1 (0.46) LMNAPMP22HDAC1HDAC6MEN1
Fumaric Acid SCHEMBL159723 0.81 MEN1 (0.46) LMNAPMP22HDAC1HDAC6MEN1
Adipic Acid SCHEMBL161400 0.80 HTR7 (0.50) HDAC1HDAC6MEN1KMT2AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012030953-A1 5-HT2C RECEPTOR AGONISTS IN THE TREATMENT OF DISORDERS AMELIORATED BY REDUCTION OF NOREPINEPHRINE LEVEL ARENA PHARMACEUTICALS, INC. (US) 2012-03-08 WO disclosed