SCHEMBL158694

SCHEMBL158694

[c]1ccc(CCc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.50
MAOB P27338 4/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50
ALOX15 P16050 1/20 0.50
ALOX12 P18054 1/20 0.50
CASP1 P29466 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 2/20 0.48
CYP2A6 P11509 1/20 0.48
HTR2A P28223 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
LOXL2 Q9Y4K0 1/20 0.48
KCNH2 Q12809 2/20 0.46
FFAR1 O14842 1/20 0.44
CALM1 P0DP23 1/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
SIGMAR1 Q99720 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27498097 0.97 MAOA (0.48) MAOAMAOBALDH1A1HPGDALOX15
SCHEMBL9863991 0.97 MAOB (0.54) MAOAMAOBALDH1A1HPGDALOX15
SCHEMBL668551 0.90 HTR2A (0.54) MAOAMAOBALDH1A1HPGDALOX15
SCHEMBL919897 0.90 MAOA (0.56) MAOAMAOBHTR2ASIGMAR1
SCHEMBL6576818 0.88 GFER (0.40) MAOAMAOBALDH1A1HPGDALOX15
SCHEMBL687989 0.87 SIGMAR1 (0.56) MAOAMAOBSIGMAR1
SCHEMBL8939756 0.87 SIGMAR1 (0.56) MAOAMAOBSIGMAR1
SCHEMBL8562894 0.85 MAOB (0.48) MAOAMAOBALDH1A1HPGDALOX15
Water SCHEMBL2780320 0.85 ALDH1A1 (0.65) MAOAMAOBALDH1A1HPGDALOX15
SCHEMBL79755 0.83 CALM1 (0.67) ALDH1A1HTR2ALOXL2CALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3966384-B1 FRESHENING COMPOSITIONS WITH ALKOXYLATED PHENOLS PROCTER & GAMBLE (US) 2023-05-03 EP claimed
EP-2708592-B2 Fabric care composition PROCTER & GAMBLE (US) 2022-03-16 EP claimed
CN-106066578-B Coloring composition, coloring cured film, color filter, display element and solid-state imaging element JSR株式会社 2021-04-13 CN claimed
CN-109401573-A A kind of polyester/GMA powdery paints 安徽省华安进出口有限公司 2019-03-01 CN claimed
CN-109385191-A A kind of scratch resistant polyester powder coating of low gloss 安徽省华安进出口有限公司 2019-02-26 CN claimed
EP-2708592-B1 Fabric care composition PROCTER & GAMBLE (US) 2019-02-13 EP claimed
CN-107853297-A A kind of farm chemical emulgent 展红明 2018-03-30 CN claimed
CN-107646876-A A kind of novel agrochemical emulsifying agent and preparation method thereof 张志坤 2018-02-02 CN claimed
CN-107518010-A A kind of non-poisonous pesticides and preparation method thereof 解丰骏 2017-12-29 CN claimed
CN-106497251-A Heat-insulated radial pattern coating of the fluorine carbon of a kind of modified zinc oxide and preparation method thereof 安徽吉思特智能装备有限公司 2017-03-15 CN claimed
CN-1329596-A Pyridinecarboxamide derivative and pest control agent containing same as active ingredient MEIJI SEIKA KAISHA (JP) 2002-01-02 CN claimed
EP-0535548-B1 Inhibitor of atherosclerotic intimal thickening NISSAN CHEMICAL IND LTD (JP) 2001-11-21 EP claimed
CN-1059777-C Urea compounded cream pesticide and producing process thereof XIBEI AGRICULTURAL UNIV (CN) 2000-12-27 CN claimed
CN-1057896-C Liquid pesticide for killing aphid and producing process thereof XIBEI AGRICULTURAL UNIV (CN) 2000-11-01 CN claimed
US-5744120-A PHOSPHINE OR ARSINE LIGATED TECHNETIUM-99M LABELED HYDRAZINO OR DIAZINO MODIFIED BIOLOGICALLY ACTIVE MOLECULES THAT SELECTIVELY LOCALIZE AT SITES OF DISEASE THE DUPONT MERICK PHARMACEUTICAL COMPANY (US) 1998-04-28 US claimed
EP-0708085-A2 Antiviral ethers of aspartate protease substrate isosteres CIBA-GEIGY AG (CH) 1996-04-24 EP claimed
EP-0404470-B1 Fragrance compositions and their use in detergent products QUEST INT (NL) 1994-04-13 EP claimed
EP-0219308-B1 2-SUBSTITUTED QUINOLINES MERCK FROSST CANADA INC. (CA) 1991-10-23 EP claimed
EP-0147191-B1 PERFUME AND COMPOSITIONS CONTAINING PERFUME UNILEVER N.V. (NL) 1989-10-04 EP claimed
US-3998802-A POLYAMIDES, CELLULOSE ESTERS, POLYESTERS, POLYACRYLONITRILES BASF AKTIENGESELLSCHAFT (DT) 1976-12-21 US claimed