Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15869752 | 0.91 | MAPT (0.56) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8419308 | 0.83 | MAPT (0.59) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL5940893 | 0.83 | MAPT (0.47) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL5940931 | 0.81 | L3MBTL1 (0.55) | MAPTTDP1L3MBTL1SMN1; SMN2CYP2C19 | |
| SCHEMBL25023083 | 0.80 | MAOA (0.49) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL31088870 | 0.80 | MAPT (0.51) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL26132599 | 0.80 | MAPT (0.51) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8756078 | 0.80 | MAPT (0.56) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL31089077 | 0.80 | LIPE (0.55) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8497192 | 0.79 | MAPT (0.65) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | PCNA, CRY1, CRY2 | MAPT 124/4885TDP1 1806/4885L3MBTL1 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.