Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17311925 | 0.84 | NOTUM (0.44) | NOTUMRAB9ANPC1BRD9L3MBTL1 | |
| SCHEMBL15875778 | 0.79 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KMT2ADRD2DRD4 | |
| SCHEMBL17311878 | 0.76 | MAOA (0.43) | NOTUMRAB9ANPC1L3MBTL1ALDH1A1 | |
| SCHEMBL15875143 | 0.75 | NPC1 (0.42) | NOTUMRAB9ANPC1CYP11B2ALDH1A1 | |
| SCHEMBL15875582 | 0.71 | HTT (0.39) | RAB9ANPC1ALDH1A1KMT2ALMNA | |
| SCHEMBL15875491 | 0.71 | ABHD16A (0.35) | ALDH1A1PTGS2 | |
| SCHEMBL15875638 | 0.71 | MGLL (0.41) | ALDH1A1KDM4ELMNA | |
| SCHEMBL6061509 | 0.69 | TAAR1 (0.47) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17311882 | 0.68 | NR3C2 (0.43) | — | |
| SCHEMBL23857027 | 0.66 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KMT2ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487516-B2 | Antibacterial oxadiazolone derivatives | ACTELION PHARMACEUTICALS, LTD. (CH) | 2016-11-08 | — | — | US | disclosed |
| US-20150353547-A1 | Antibacterial Oxadiazolone Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-12-10 | — | — | US | disclosed |
| EP-2943492-A1 | ANTIBACTERIAL OXADIAZOLONE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2015-11-18 | — | — | EP | disclosed |
| EP-2943227-A1 | TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS | Molecular Insight Pharmaceuticals (US) | 2015-11-18 | — | — | EP | disclosed |
| WO-2014110372-A1 | TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS | MOLECULAR INSIGHT PHARMACEUTICALS (US) | 2014-07-17 | — | — | WO | disclosed |
| WO-2014108836-A1 | ANTIBACTERIAL OXADIAZOLONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2014-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353547-A1 | Antibacterial Oxadiazolone Derivatives | OXA1L, PYM1, XDH | NOTUM 3259/4885RAB9A 3069/4885NPC1 2275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.