Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | RAD52 | P43351 | 1/20 | 0.58 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CRY1 | Q16526 | 3/20 | 0.50 |
| ▸ | CRY2 | Q49AN0 | 3/20 | 0.50 |
| ▸ | PER2 | O15055 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16604024 | 0.85 | RAD52 (0.74) | DNM1SMN1; SMN2MAPTRAD52NLRP1 | |
| SCHEMBL28586701 | 0.85 | TSHR (0.65) | DNM1SMN1; SMN2MAPTRAD52NLRP1 | |
| SCHEMBL21467809 | 0.83 | DNM1 (0.71) | DNM1SMN1; SMN2MAPTALDH1A1CRY1 | |
| Wiskostatin SCHEMBL21067493 | 0.82 | DNM1 (1.00) | DNM1SMN1; SMN2MAPTRAD52LMNA | |
| Wiskostatin SCHEMBL5800361 | 0.82 | DNM1 (1.00) | DNM1SMN1; SMN2MAPTRAD52LMNA | |
| Wiskostatin SCHEMBL29911343 | 0.82 | DNM1 (1.00) | DNM1SMN1; SMN2MAPTRAD52LMNA | |
| SCHEMBL14706715 | 0.81 | RAD52 (0.64) | DNM1SMN1; SMN2MAPTRAD52NLRP1 | |
| SCHEMBL6823233 | 0.77 | RAD52 (0.86) | MAPTRAD52NLRP1LMNAALDH1A1 | |
| SCHEMBL17221871 | 0.77 | RAD52 (0.59) | DNM1SMN1; SMN2MAPTRAD52NLRP1 | |
| SCHEMBL17482005 | 0.77 | RAD52 (0.56) | DNM1SMN1; SMN2MAPTRAD52NLRP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518750-B | Carbazole amino alcohol compound, preparation method thereof and application of carbazole amino alcohol compound in resisting parasitic diseases | 中国疾病预防控制中心寄生虫病预防控制所 | 2021-06-01 | — | — | CN | claimed |
| CN-106518750-B | Carbazole amino alcohol compound, preparation method thereof and application of carbazole amino alcohol compound in resisting parasitic diseases | 中国疾病预防控制中心寄生虫病预防控制所 | 2021-06-01 | — | — | CN | disclosed |
| US-10947188-B2 | Small molecule ferroptosis inducers | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-03-16 | — | — | US | disclosed |
| US-10730848-B2 | Protective molecules against anthrax toxin | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-04 | — | — | US | disclosed |
| US-20160016930-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-21 | — | — | US | disclosed |
| WO-2014113607-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947188-B2 | Small molecule ferroptosis inducers | GPX4, AIFM2, GPX1 | DNM1 2882/4885SMN1; SMN2 4526/4885MAPT 4344/4885 |
| US-20160016930-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | ANTXR2, TSG101, ANXA1 | DNM1 2869/4885SMN1; SMN2 3581/4885MAPT 4617/4885 |
| US-10730848-B2 | Protective molecules against anthrax toxin | ANTXR2, TSG101, ANXA1 | DNM1 2869/4885SMN1; SMN2 3581/4885MAPT 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.