SCHEMBL15899323

SCHEMBL15899323

COCCc1cccc(OC(=O)O)c1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.40
KDM4E B2RXH2 4/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
TP53 P04637 1/20 0.38
TACR1 P25103 1/20 0.37
FABP3 P05413 1/20 0.37
FABP4 P15090 1/20 0.37
FABP5 Q01469 1/20 0.37
TSHR P16473 1/20 0.37
GAA P10253 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TAAR1 Q96RJ0 1/20 0.36
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15899597 0.86 L3MBTL1 (0.38) HTTKDM4EL3MBTL1FABP3FABP4
SCHEMBL1834263 0.85 LTB4R (0.41) HTTKDM4EFABP3FABP4FABP5
SCHEMBL15899312 0.85 KDM4E (0.37) KDM4EL3MBTL1GAAALDH1A1
SCHEMBL2536888 0.85 MTNR1A (0.44) HTTKDM4ETSHRTAAR1MTNR1A
SCHEMBL15899560 0.84 L3MBTL1 (0.36) KDM4EL3MBTL1GAAALDH1A1
SCHEMBL1839146 0.83 MAPT (0.39) HTTKDM4EL3MBTL1FABP3FABP4
SCHEMBL1840917 0.83 PPARA (0.48) KDM4E
SCHEMBL15899315 0.82 MAPT (0.36) HTTKDM4EALDH1A1CHRM5CHRM1
SCHEMBL1156862 0.82 PPARA (0.53)
SCHEMBL15225795 0.81 ADRB2 (0.40) HTTKDM4EL3MBTL1TP53GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2759552-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO LTD (JP) 2016-02-10 EP disclosed
US-9243081-B2 Solid catalyst component for polymerization of olefin, catalyst for polymerization of olefin, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2016-01-26 US disclosed
US-20140343237-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO., LTD. (JP) 2014-11-20 US disclosed
EP-2759552-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER Toho Titanium CO., LTD. (JP) 2014-07-30 EP disclosed