Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760358 | 0.83 | HRH3 (0.43) | HRH3 | |
| SCHEMBL26725202 | 0.82 | HRH3 (0.46) | HRH3 | |
| SCHEMBL3345211 | 0.82 | HRH3 (0.46) | HRH3 | |
| SCHEMBL3347181 | 0.79 | HRH3 (0.40) | HRH3 | |
| SCHEMBL14557432 | 0.78 | HTR1A (0.45) | HRH3MAPT | |
| SCHEMBL2482261 | 0.77 | HRH3 (0.43) | HRH3 | |
| SCHEMBL29626142 | 0.77 | HTR1A (0.44) | HRH3 | |
| SCHEMBL15904342 | 0.77 | HRH3 (0.41) | HRH3MAPTTSHRGFER | |
| SCHEMBL3263872 | 0.75 | HRH3 (0.43) | HRH3 | |
| Hydrochloric Acid SCHEMBL10806950 | 0.75 | HTR1A (0.42) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041454-A | Stimulate gastrointestinal motility | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-20 | — | — | US | disclosed |
| US-4975439-A | Gastrointestinal motility stimulating properties | JANSSEN PHARMACEUTICAL N.V. (BE) | 1990-12-04 | — | — | US | disclosed |