Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760358 | 0.98 | HRH3 (0.43) | HRH3 | |
| SCHEMBL3347181 | 0.94 | HRH3 (0.40) | HRH3 | |
| SCHEMBL26725202 | 0.84 | HRH3 (0.46) | HRH3ALDH1A1 | |
| SCHEMBL15904342 | 0.83 | HRH3 (0.41) | HRH3ALDH1A1 | |
| SCHEMBL3315257 | 0.82 | HRH3 (0.35) | HRH3 | |
| SCHEMBL18389972 | 0.82 | HTR1A (0.53) | HRH3ALDH1A1 | |
| SCHEMBL9760411 | 0.82 | HRH3 (0.44) | HRH3 | |
| SCHEMBL3347099 | 0.81 | CA2 (0.39) | HRH3 | |
| SCHEMBL3317327 | 0.81 | HRH3 (0.38) | HRH3 | |
| SCHEMBL2482261 | 0.79 | HRH3 (0.43) | HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010049731-A1 | PYRAZOLO- AND IMIDAZOPYRIDINYLPYRIMIDINEAMINES AS IGF-1R TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | WO | claimed |
| EP-1250332-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | Abbott Laboratories (US) | 2002-10-23 | — | — | EP | claimed |
| WO-2001044223-A1 | INHIBITORS OF INTERLEUKIN 5 GENE EXPRESSION | ABBOTT LABORATORIES (US) | 2001-06-21 | — | — | WO | claimed |
| WO-2010049731-A1 | PYRAZOLO- AND IMIDAZOPYRIDINYLPYRIMIDINEAMINES AS IGF-1R TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | WO | disclosed |