Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237591 | 0.86 | TBXAS1 (0.59) | TBXAS1FFAR1CYP3A4PTGS1PTGS2 | |
| SCHEMBL17108794 | 0.84 | TBXAS1 (0.48) | TBXAS1FFAR1IDO1EPHX2PPARG | |
| SCHEMBL15905959 | 0.82 | PTGS2 (0.55) | TBXAS1FFAR1EPHX2PPARGCYP3A4 | |
| SCHEMBL15905960 | 0.81 | FFAR1 (0.47) | TBXAS1FFAR1EPHX2PPARGCYP3A4 | |
| SCHEMBL19553694 | 0.80 | PTGS1 (0.66) | TBXAS1PTGS1PTGS2LMNACYP2C9 | |
| SCHEMBL11647879 | 0.79 | TBXAS1 (0.53) | TBXAS1FFAR1PPARGALDH1A1PTGS1 | |
| SCHEMBL12696346 | 0.79 | TBXAS1 (0.53) | TBXAS1FFAR1PPARGPTGS1PTGS2 | |
| SCHEMBL10081972 | 0.79 | TBXAS1 (0.53) | TBXAS1FFAR1PPARGPTGS1PTGS2 | |
| SCHEMBL1410416 | 0.79 | TBXAS1 (0.53) | TBXAS1FFAR1PPARGCYP3A4PTGS1 | |
| SCHEMBL11996333 | 0.79 | TBXAS1 (0.53) | TBXAS1FFAR1PPARGALDH1A1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637441-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| US-8791231-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2014-07-29 | — | — | US | disclosed |