Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237591 | 0.84 | TBXAS1 (0.59) | TBXAS1FFAR1CYP3A4PTGS1PTGS2 | |
| SCHEMBL15905958 | 0.84 | TBXAS1 (0.49) | TBXAS1FFAR1IDO1EPHX2PPARG | |
| SCHEMBL15905959 | 0.81 | PTGS2 (0.55) | TBXAS1FFAR1EPHX2PPARGCYP3A4 | |
| SCHEMBL17108793 | 0.80 | EPHX2 (0.44) | TBXAS1FFAR1EPHX2PPARGPTGS1 | |
| SCHEMBL12611746 | 0.80 | SLC7A5 (0.65) | CYP3A4ALDH1A1MAPTPTGS1PTGS2 | |
| SCHEMBL8237191 | 0.80 | SLC7A5 (0.65) | CYP3A4ALDH1A1MAPTPTGS1PTGS2 | |
| SCHEMBL12200630 | 0.79 | TBXAS1 (0.51) | TBXAS1FFAR1PTGS1PTGS2LMNA | |
| SCHEMBL15568884 | 0.79 | TBXAS1 (0.51) | TBXAS1FFAR1PTGS1PTGS2LMNA | |
| SCHEMBL16017643 | 0.79 | TBXAS1 (0.51) | TBXAS1FFAR1PTGS1PTGS2LMNA | |
| SCHEMBL28052529 | 0.79 | TBXAS1 (0.51) | TBXAS1FFAR1PTGS1PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015143224-A1 | CHIMERIC ANTIGEN RECEPTOR-MODIFIED T-CELLS | AMBRX, INC. (US) | 2015-09-24 | — | — | WO | disclosed |