Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237591 | 0.82 | TBXAS1 (0.59) | FFAR1TBXAS1LDHACYP3A4TSHR | |
| SCHEMBL15905958 | 0.81 | TBXAS1 (0.49) | FFAR1TBXAS1PPARAPPARDPPARG | |
| SCHEMBL17108794 | 0.79 | TBXAS1 (0.48) | FFAR1TBXAS1PPARAPPARDPPARG | |
| SCHEMBL15905959 | 0.78 | PTGS2 (0.55) | FFAR1TBXAS1PPARAPPARDPPARG | |
| SCHEMBL22751983 | 0.78 | LOXL2 (0.56) | TBXAS1LDHAPPARGEPHX2TSHR | |
| SCHEMBL23582892 | 0.78 | LOXL2 (0.56) | TBXAS1LDHAPPARGEPHX2TSHR | |
| SCHEMBL13577833 | 0.78 | LOXL2 (0.56) | TBXAS1LDHAPPARGEPHX2TSHR | |
| SCHEMBL663059 | 0.77 | LDHA (0.73) | FFAR1PPARALDHAPPARG | |
| SCHEMBL8283100 | 0.77 | LDHA (0.73) | FFAR1PPARALDHAPPARG | |
| SCHEMBL19553694 | 0.76 | PTGS1 (0.66) | TBXAS1TSHRCXCR1CXCR2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791231-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2014-07-29 | — | — | US | disclosed |