Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237591 | 0.83 | TBXAS1 (0.59) | PTGS2LMNACYP1A2TBXAS1FFAR1 | |
| SCHEMBL15905958 | 0.82 | TBXAS1 (0.49) | PTGS2LMNAALDH1A1TBXAS1FFAR1 | |
| SCHEMBL17108794 | 0.81 | TBXAS1 (0.48) | PTGS2LMNAALDH1A1TBXAS1FFAR1 | |
| SCHEMBL27674018 | 0.79 | TBXAS1 (0.49) | PTGS2LMNATBXAS1FFAR1EPHX2 | |
| SCHEMBL15905960 | 0.78 | FFAR1 (0.47) | PTGS2LMNAALDH1A1ALOX15TBXAS1 | |
| SCHEMBL19553694 | 0.77 | PTGS1 (0.66) | PTGS2LMNATBXAS1PTGS1CYP2C9 | |
| SCHEMBL11647879 | 0.76 | TBXAS1 (0.53) | PTGS2LMNAALDH1A1TBXAS1FFAR1 | |
| SCHEMBL12696346 | 0.76 | TBXAS1 (0.53) | PTGS2LMNATBXAS1FFAR1PPARG | |
| SCHEMBL10081972 | 0.76 | TBXAS1 (0.53) | PTGS2LMNATBXAS1FFAR1PPARG | |
| SCHEMBL1410416 | 0.76 | TBXAS1 (0.53) | PTGS2LMNATBXAS1FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791231-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2014-07-29 | — | — | US | disclosed |