Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20792927 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1NPSR1L3MBTL1 | |
| SCHEMBL31575357 | 0.94 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1NPSR1L3MBTL1 | |
| SCHEMBL22059743 | 0.91 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1NPSR1L3MBTL1 | |
| SCHEMBL26419124 | 0.90 | MEN1 (0.59) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL26327468 | 0.88 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1NPSR1L3MBTL1 | |
| SCHEMBL15105924 | 0.87 | CHRM3 (0.46) | ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL23277976 | 0.86 | SIGMAR1 (0.46) | ALDH1A1KMT2AMEN1NPSR1L3MBTL1 | |
| SCHEMBL22618156 | 0.85 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1NPSR1L3MBTL1 | |
| SCHEMBL5827412 | 0.85 | L3MBTL1 (0.55) | ALDH1A1KMT2AMEN1NPSR1L3MBTL1 | |
| SCHEMBL20054721 | 0.81 | HTR2C (0.45) | ALDH1A1KMT2AMEN1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133194-B2 | Cyclic tripeptide mimetics as plasmin inhibitors | STEINMETZER TORSTEN (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9133194-B2 | Cyclic tripeptide mimetics as plasmin inhibitors | STEINMETZER TORSTEN (DE) | 2015-09-15 | — | — | US | disclosed |
| EP-2729484-B1 | CYCLIC TRIPEPTIDE MIMETICS AS PLASMIN INHIBITORS | PHILIPPS UNIVERSITÄT MARBURG (DE) | 2015-07-29 | — | — | EP | disclosed |
| US-20140213781-A1 | CYCLIC TRIPEPTIDE MIMETICS AS PLASMIN INHIBITORS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2014-07-31 | — | — | US | disclosed |
| US-20140213781-A1 | CYCLIC TRIPEPTIDE MIMETICS AS PLASMIN INHIBITORS | PHILIPPS-UNIVERSITÄT MARBURG (DE) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213781-A1 | CYCLIC TRIPEPTIDE MIMETICS AS PLASMIN INHIBITORS | F2, FGB, SERPINC1 | ALDH1A1 4699/4885KMT2A 4137/4885MEN1 679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.