SCHEMBL15908730

SCHEMBL15908730

CCOC(=O)c1cc2cc(Br)ccc2n1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.49
MCL1 Q07820 1/20 0.48
ELANE P08246 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
ALDH1A1 P00352 3/20 0.46
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42
GABRA3 P34903 1/20 0.42
GABRB2 P47870 1/20 0.42
MAPT P10636 3/20 0.42
ATM Q13315 1/20 0.42
NOD2 Q9HC29 2/20 0.41
NOD1 Q9Y239 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HTT P42858 1/20 0.41
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17323081 0.86 MAPT (0.53) LMNAELANESMN1; SMN2ALDH1A1MAPT
SCHEMBL1096993 0.84 MCL1 (0.64) LMNAMCL1ELANESMN1; SMN2ALDH1A1
SCHEMBL17323111 0.84 LMNA (0.47) LMNAELANESMN1; SMN2ALDH1A1MAPT
SCHEMBL31435629 0.84 MCL1 (0.64) LMNAMCL1ELANESMN1; SMN2ALDH1A1
SCHEMBL16792772 0.84 LMNA (0.50) LMNAMCL1ELANESMN1; SMN2ALDH1A1
SCHEMBL1968469 0.83 NOD2 (0.49) LMNAELANESMN1; SMN2ALDH1A1MAPT
SCHEMBL15908740 0.83 NOD2 (0.49) LMNASMN1; SMN2ALDH1A1MAPTNOD2
SCHEMBL7488350 0.83 LMNA (0.52) LMNAMCL1ELANESMN1; SMN2ALDH1A1
SCHEMBL17327016 0.82 L3MBTL1 (0.55) LMNAELANESMN1; SMN2ALDH1A1MAPT
SCHEMBL17323107 0.82 CA12 (0.47) SMN1; SMN2ALDH1A1MAPTATMNOD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9447105-B2 Triazine compounds and a process for preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-09-20 US disclosed
US-20150353566-A1 TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-12-10 US disclosed
WO-2014115171-A1 TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-07-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150353566-A1 TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF TPH2, IDO2, INMT LMNA 1199/4885MCL1 1727/4885ELANE 4537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.