SCHEMBL17849694

SCHEMBL17849694

CC1(C)c2cccc3ccc4cc(-c5ccc6cc(Br)ccc6c5)cc1c4c23

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.41
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35
PTPN1 P18031 1/20 0.34
PTPN6 P29350 1/20 0.34
CDC25A P30304 1/20 0.34
PGR P06401 2/20 0.34
PLAU P00749 1/20 0.34
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
SIRT2 Q8IXJ6 1/20 0.31
BIRC5 O15392 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13888836 0.91 MAOB (0.34) CYP2A6LPLLIPGPGRALDH1A1
SCHEMBL17849698 0.91 MAOB (0.34) CYP2A6LPLLIPGPGRALDH1A1
SCHEMBL15909678 0.85 LPL (0.43) CYP2A6CYP11B1CYP11B2LPLLIPG
SCHEMBL12982875 0.83 NPSR1 (0.40) CYP2A6MEN1KMT2AKDM4EALDH1A1
SCHEMBL15731073 0.83 PGR (0.34) CYP2A6CYP11B1CYP11B2LPLLIPG
SCHEMBL15854456 0.82 LPL (0.35) CYP2A6CYP11B1CYP11B2LPLLIPG
SCHEMBL17849711 0.81 BIRC5 (0.32) CYP11B1CYP11B2ALDH1A1NPSR1BIRC5
SCHEMBL17849710 0.80 MEN1 (0.34) MEN1KMT2AMAPTBIRC5
SCHEMBL17849691 0.79 ALDH1A1 (0.48) CYP11B1CYP11B2LPLLIPGMEN1
SCHEMBL17849633 0.78 LPL (0.35) LPLLIPGHSD17B1HSD17B2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed