SCHEMBL15909679

SCHEMBL15909679

CC1(C)c2cc(-c3ccc4ccccc4c3)cc3ccc4cc(-c5ccc(Br)c6ccccc56)cc1c4c23

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.38
LIPG Q9Y5X9 1/20 0.38
GSTP1 P09211 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
CHRNA1 P02708 1/20 0.33
CHRNG P07510 1/20 0.33
CHRNB1 P11230 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA4 P43681 1/20 0.33
CHRND Q07001 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17849702 0.88 CYP1A2 (0.35) CYP1A2CYP2D6CYP2C19
SCHEMBL17849709 0.82 TYMS (0.34) CYP1A2
SCHEMBL15909678 0.81 LPL (0.43) LPLLIPGGSTP1SIRT2ESR1
SCHEMBL24871313 0.79 ESR1 (0.48) LPLLIPGGSTP1SIRT2ESR1
SCHEMBL29541386 0.79 GSTP1 (0.52) GSTP1ESR1ESR2SLC6A2SLC6A4
SCHEMBL2164353 0.79 GSTP1 (0.52) GSTP1ESR1ESR2SLC6A2SLC6A4
SCHEMBL12781908 0.77 PDK2 (0.35) CYP1A2
SCHEMBL12192934 0.76 HSD17B1 (0.47) GSTP1SIRT2ESR1ESR2CA1
SCHEMBL15731070 0.76 CYP1A2 (0.47) CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL17849708 0.74 CYP1A2 (0.37) CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140209872-A1 COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed
US-20140209872-A1 COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed