Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | QPCT | Q16769 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15356790 | 0.88 | QPCT (0.41) | PRMT5RIPK2HTTQPCTALDH1A1 | |
| SCHEMBL16562798 | 0.88 | RIPK2 (0.38) | PRMT5RIPK2HTTQPCTDGAT1 | |
| SCHEMBL15356856 | 0.87 | QPCT (0.40) | PRMT5RIPK2HTTQPCTKDM4E | |
| SCHEMBL4969169 | 0.84 | HTT (0.39) | PRMT5RIPK2HTTALDH1A1DGAT1 | |
| SCHEMBL15357519 | 0.81 | DGAT1 (0.37) | RIPK2HTTQPCTALDH1A1DGAT1 | |
| SCHEMBL18024988 | 0.81 | DGAT1 (0.37) | PRMT5HTTQPCTALDH1A1DGAT1 | |
| SCHEMBL2730846 | 0.81 | HTT (0.48) | PRMT5RIPK2HTTALDH1A1CYP2A6 | |
| SCHEMBL15356762 | 0.79 | ALDH1A1 (0.38) | PRMT5RIPK2HTTALDH1A1CYP2A6 | |
| SCHEMBL15975575 | 0.78 | HTT (0.37) | PRMT5RIPK2HTTALDH1A1DGAT1 | |
| SCHEMBL14904596 | 0.78 | ALDH1A1 (0.35) | PRMT5RIPK2HTTALDH1A1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10165775-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2019-01-01 | — | — | US | disclosed |
| US-9708288-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-07-18 | — | — | US | disclosed |
| US-9708288-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-07-18 | — | — | US | disclosed |
| US-9655365-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-9655365-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-05-23 | — | — | US | disclosed |
| US-9591857-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-03-14 | — | — | US | disclosed |
| US-9591857-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2017-03-14 | — | — | US | disclosed |
| US-9422278-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-08-23 | — | — | US | disclosed |
| US-9422278-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-08-23 | — | — | US | disclosed |
| US-9282739-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-03-15 | — | — | US | disclosed |
| US-8937083-B2 | Pesticidal compositions and processes related thereto | DowAgroSciences, LLC (US) | 2015-01-20 | — | — | US | disclosed |
| US-8937083-B2 | Pesticidal compositions and processes related thereto | DowAgroSciences, LLC (US) | 2015-01-20 | — | — | US | disclosed |
| US-8901153-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8901153-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-8815271-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-8815271-B2 | Pesticidal compositions and processes related thereto | DOW AGROSCIENCES, LLC. (US) | 2014-08-26 | — | — | US | disclosed |
| US-20140213448-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213448-A1 | PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO | ACHE, DDT, PTMS | PRMT5 1049/4885RIPK2 2576/4885HTT 4384/4885 |
| US-10165775-B2 | Pesticidal compositions and processes related thereto | ACHE, DDT, PTMS | PRMT5 1049/4885RIPK2 2576/4885HTT 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.