SCHEMBL15910951

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30168569	1.00	CHEK1 (0.49)	CHEK1AURKADAPK3CSNK1A1GSK3A
	SCHEMBL25917046	0.86	CHEK1 (0.50)	CHEK1AURKADAPK3CSNK1A1GSK3A
	SCHEMBL30168550	0.86	CHEK1 (0.38)	CHEK1AURKADAPK3CSNK1A1GSK3A
	SCHEMBL15910832	0.86	CHEK1 (0.38)	CHEK1AURKADAPK3CSNK1A1GSK3A
	SCHEMBL3699781	0.82	CHEK1 (0.53)	CHEK1AURKADAPK3CSNK1A1GSK3A
	SCHEMBL25512215	0.80	HDAC8 (0.46)	HTR2AHTR2CMAPTCYP1A2TGFBR1
	SCHEMBL25273130	0.79	CHEK1 (0.54)	CHEK1AURKADAPK3CSNK1A1GSK3A
	SCHEMBL23886616	0.79	HDAC8 (0.48)	HTR2AHTR2CROCK1CYP1A2TGFBR1
	SCHEMBL31097149	0.78	HDAC8 (0.38)	HTR2AHTR2CROCK1CYP1A2TGFBR1
	SCHEMBL21509551	0.76	NR3C1 (0.38)	HTR2AHTR2CRAB9ACYP1A2TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.