SCHEMBL159149

SCHEMBL159149

CN1C(=O)CCC1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACE P12821 2/20 0.47
P2RX7 Q99572 18/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1850331 1.00 ACE (0.47) ACEP2RX7
SCHEMBL1587617 1.00 ACE (0.47) ACEP2RX7
SCHEMBL647325 1.00 ACE (0.47) ACEP2RX7
Ammonia Solution, Strong SCHEMBL11295703 0.98 ACE (0.46) ACEP2RX7
SCHEMBL16339447 0.88 P2RX7 (0.44) ACEP2RX7
SCHEMBL30813130 0.88 P2RX7 (0.44) ACEP2RX7
SCHEMBL16339048 0.88 P2RX7 (0.44) ACEP2RX7
SCHEMBL18212792 0.86 ACE (0.44) ACEP2RX7
SCHEMBL13949148 0.83 P2RX7 (0.45) P2RX7
SCHEMBL18101128 0.83 P2RX7 (0.45) P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130338193-A1 CHIRAL 1-(4-METHYLPHENYLMETHYL)-5-OXO--PYRROLIDINE-2-CARBOXAMIDES AS INHIBITORS OF COLLAGEN INDUCED PLATELET ACTIVATION AND ADHESION COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-12-19 US claimed
US-20100163070-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBRES USING HEATING MEANS AND AN AMIDE L'OREAL S.A. (FR) 2010-07-01 US claimed
US-20100065492-A1 Compositions And Methods For Separating Enantiomers WATERS TECHNOLOGIES CORPORATION (US) 2010-03-18 US claimed
US-7628920-B2 Compositions and methods for separating enantiomers WATERS TECHNOLOGIES CORPORATION (US) 2009-12-08 US claimed
US-20080237130-A1 Compositions and Methods for Separating Enantiomers WATERS INVESTMENTS LIMITED (US) 2008-10-02 US claimed
JP-2007532880-A 2007-11-15 JP claimed
WO-2005099855-A1 COMPOSITIONS AND METHODS FOR SEPARATING ENANTIOMERS WATERS INVESTMENTS LIMITED (US) 2005-10-27 WO claimed
WO-2005094854-A1 MODIFIED NUTRACEUTICAL COMPOSITION TORBANGUN PTY LTD (AU) 2005-10-13 WO claimed
US-3953352-A COATING A PYRROLIDONE-CARBOXYLIC ACID COMPOUND KAO SOAP CO., LTD. (JA) 1976-04-27 US claimed
JP-57170146-A None JP disclosed
EP-3985001-B1 PHARMACEUTICAL COMPOSITION FOR USE IN TREATING A CANCER SERVIER LAB (FR) 2026-04-29 EP disclosed
US-20260109709-A1 2-AMINO IMIDAZOLE DERIVATIVES AS PRMT5 INHIBITORS MIRATI THERAPEUTICS INC (US) 2026-04-23 US disclosed
EP-4631573-A2 TEAD INHIBITORS Orion Corporation (FI) 2025-10-15 EP disclosed
EP-4323338-B1 TEAD INHIBITORS ORION CORP (FI) 2025-10-08 EP disclosed
JP-S57170146-A CENTRAL SYRUP FOR CONFECTION LOTTE CO LTD 1982-10-20 JP disclosed
US-4220168-A Method of moisturizing and maintaining normal moisture level in hair having a normal moisture content HELENE CURTIS INDUSTRIES, INC. (US) 1980-09-02 US disclosed
US-4220166-A Method of restoring normal moisture level to hair with severe moisture deficiency HELENE CURTIS INDUSTRIES, INC. (US) 1980-09-02 US disclosed
US-4220167-A Method of restoring normal moisture level to hair with slight to moderate moisture deficiency HELENE CURTIS INDUSTRIES, INC. (US) 1980-09-02 US disclosed
US-3953352-A COATING A PYRROLIDONE-CARBOXYLIC ACID COMPOUND KAO SOAP CO., LTD. (JA) 1976-04-27 US disclosed
US-3932622-A WATER-IN-OIL EMULSION, DISODIUM OR DIPOTASSIUM SALT OF N-ACETYLGLUTAMTIC ACID GENERAL FOODS CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109709-A1 2-AMINO IMIDAZOLE DERIVATIVES AS PRMT5 INHIBITORS PRMT5, PRMT1, PRMT3 ACE 4036/4885P2RX7 4335/4885
US-20130338193-A1 CHIRAL 1-(4-METHYLPHENYLMETHYL)-5-OXO--PYRROLIDINE-2-CARBOXAMIDES AS INHIBITORS OF COLLAGEN INDUCED PLATELET ACTIVATION AND ADHESION PLOD1, PLOD3, PLOD2 ACE 3663/4885P2RX7 628/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.