Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15904952 | 0.92 | KMT2A (0.38) | KMT2AKCNQ1GYS1RAB9AGALR3 | |
| Hydrochloric Acid SCHEMBL17313712 | 0.92 | KMT2A (0.37) | KMT2AKCNQ1GYS1RAB9AGALR3 | |
| SCHEMBL15919486 | 0.91 | KMT2A (0.36) | KMT2AKCNQ1GYS1RAB9AGALR3 | |
| SCHEMBL17327495 | 0.91 | TDP1 (0.37) | KMT2AKCNQ1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15919380 | 0.90 | GYS1 (0.33) | KMT2AGYS1ALDH1A1MAPTMEN1 | |
| SCHEMBL17327552 | 0.88 | ALDH1A1 (0.38) | KMT2AALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL15919653 | 0.88 | PREP (0.37) | KMT2AKCNQ1GYS1RAB9AGALR3 | |
| SCHEMBL17327509 | 0.88 | TDP1 (0.34) | KMT2AKCNQ1GYS1ALDH1A1MAPT | |
| SCHEMBL15919288 | 0.87 | GYS1 (0.35) | KMT2AGYS1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL15919492 | 0.86 | ROCK2 (0.38) | KMT2AKCNQ1RAB9AGALR3NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663488-B2 | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | Viamet Pharmaceuticals (NC), Inc. | 2015-12-10 | — | — | US | disclosed |
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353546-A1 | METALLOENZYME INHIBITOR COMPOUNDS | MMEL1, GPX1, MPO | KMT2A 1886/4885KCNQ1 2088/4885GYS1 2885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.