Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.54 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919857 | 0.88 | MAPT (0.70) | FAAHNPY2RCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL15919867 | 0.86 | NPY2R (0.73) | NPY2RKMT2AMAPTMEN1LMNA | |
| SCHEMBL15920163 | 0.85 | NPY2R (0.76) | FAAHNPY2RCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL15920165 | 0.85 | CACNA2D1 (0.68) | FAAHCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL15920168 | 0.84 | CACNA2D1 (0.61) | FAAHCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL15920269 | 0.82 | CA12 (0.64) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL15920162 | 0.78 | FAAH (0.60) | FAAHCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL3604234 | 0.78 | FAAH (1.00) | FAAHMAPT | |
| SCHEMBL15920004 | 0.78 | FAAH (0.59) | FAAHKMT2AMAPTPDGFRBMEN1 | |
| SCHEMBL13097610 | 0.77 | POLB (0.58) | FAAHKMT2AMAPTPDGFRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |