Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.61 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.61 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.56 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920165 | 0.90 | CACNA2D1 (0.68) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL15920269 | 0.88 | CA12 (0.64) | CACNA2D1CACNA1BCACNB1CACNA1CGAA | |
| SCHEMBL15919857 | 0.86 | MAPT (0.70) | CACNA2D1CACNA1BCACNB1CACNA1CGAA | |
| SCHEMBL15920167 | 0.84 | FAAH (0.64) | CACNA2D1CACNA1BCACNB1CACNA1CGAA | |
| SCHEMBL15920162 | 0.83 | FAAH (0.60) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL31350655 | 0.83 | CACNA2D1 (0.53) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL31350846 | 0.83 | CACNA2D1 (0.53) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL15920163 | 0.83 | NPY2R (0.76) | CACNA2D1CACNA1BCACNB1CACNA1CKMT2A | |
| SCHEMBL27652942 | 0.82 | NPC1 (0.83) | GAAKMT2ANPC1RAB9AFAAH | |
| SCHEMBL19231602 | 0.81 | NPC1 (0.67) | GAAKMT2ANPC1RAB9AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |