SCHEMBL1592472

SCHEMBL1592472

C=CC(=O)OCc1cccc(Cl)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.68
MMP1 P03956 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
MMP12 P39900 1/20 0.52
CYP3A4 P08684 2/20 0.50
IDO1 P14902 2/20 0.50
AGXT P21549 2/20 0.50
RXRA P19793 1/20 0.49
RXRB P28702 1/20 0.49
RXRG P48443 1/20 0.49
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 1/20 0.48
TSHR P16473 1/20 0.48
MAOA P21397 3/20 0.48
MAOB P27338 3/20 0.48
NR4A2 P43354 1/20 0.48
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL227301 0.88 HCAR2 (0.51) HCAR2CYP3A4ALDH1A1TSHRTHRB
SCHEMBL29908312 0.84 HCAR2 (0.50) HCAR2ALDH1A1TSHRTHRBHPGD
SCHEMBL150216 0.84 HCAR2 (0.50) HCAR2ALDH1A1TSHRTHRBHPGD
SCHEMBL24172399 0.84 HCAR2 (0.49) HCAR2MMP1MMP2MMP9MMP12
SCHEMBL1898363 0.83 HCAR2 (0.48) HCAR2THRB
SCHEMBL9555012 0.82 HCAR2 (0.47) HCAR2CYP3A4ALDH1A1TSHRTHRB
SCHEMBL2029341 0.82 IDO1 (0.51) HCAR2IDO1MAOAMAOBTHRB
SCHEMBL24270436 0.82 HCAR2 (0.47) HCAR2TSHRTHRBHTT
SCHEMBL27781513 0.82 HCAR2 (0.48) HCAR2CYP3A4ALDH1A1TSHRTHRB
SCHEMBL11739714 0.81 HCAR2 (0.74) HCAR2MMP1MMP2MMP9MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12186974-B2 Method of manufacturing a heat-shrink elastomeric element HALLIBURTON ENERGY SERVICES, INC. (US) 2025-01-07 US disclosed
CN-116262727-A Tetra-substituted styrene axial chiral compound and synthesis method thereof 南京理工大学 2023-06-16 CN disclosed
US-20230174506-A1 (DI)AMINATION OF ACTIVATED ALLENE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS FOR SYNTHESIS OF THE SAME PURDUE RESEARCH FOUNDATION 2023-06-08 US disclosed
US-20210323217-A1 METHOD OF MANUFACTURING A HEAT-SHRINK ELASTOMERIC ELEMENT HALLIBURTON ENERGY SERVICES, INC. 2021-10-21 US disclosed
US-11065807-B2 Method of manufacturing a heat-shrink elastomeric element THE UNIVERSITY OF TEXAS SYSTEM BOARD OF REGENTS (US) 2021-07-20 US disclosed
US-20190077070-A1 HEAT-SHRINK ELASTOMERIC ELEMENTS MADE FROM SHAPE MEMORY POLYMERS HALLIBURTON ENERGY SERVICES, INC. 2019-03-14 US disclosed
US-8299191-B2 Shape memory polymers and process for preparing GEORGIA TECH RESEARCH CORP. (US) 2012-10-30 US disclosed
EP-2491082-A1 SHAPE MEMORY POLYMERS AND PROCESS FOR PREPARING Georgia Tech Research Corporation (US) 2012-08-29 EP disclosed
WO-2011049879-A1 SHAPE MEMORY POLYMERS AND PROCESS FOR PREPARING GEORGIA TECH RESEARCH CORPORATION (US) 2011-04-28 WO disclosed
US-20110092652-A1 SHAPE MEMORY POLYMERS AND PROCESS FOR PREPARING GEORGIA TECH RESEARCH CORPORATION 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174506-A1 (DI)AMINATION OF ACTIVATED ALLENE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS FOR SYNTHESIS OF THE SAME NAAA, PAM, AANAT HCAR2 1404/4885MMP1 4555/4885MMP2 4580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.