SCHEMBL1592846

SCHEMBL1592846

O=S(=O)(Nc1ccccc1Cl)c1ccc(O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.71
MEN1 O00255 2/20 0.71
KMT2A Q03164 2/20 0.71
GRM4 Q14833 4/20 0.57
KDM4E B2RXH2 1/20 0.56
PTK2B Q14289 1/20 0.56
PKM P14618 1/20 0.56
GPR27 Q9NS67 1/20 0.54
ERBB2 P04626 1/20 0.54
HSP90AA1 P07900 1/20 0.54
HSP90AB1 P08238 1/20 0.54
ALDH1A1 P00352 1/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
MAPK1 P28482 1/20 0.53
HTT P42858 1/20 0.53
RECQL P46063 1/20 0.53
UQCRB P14927 1/20 0.53
TUBB4A P04350 1/20 0.52
TUBB P07437 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14601529 0.87 TUBB4A (0.63) TSHRMEN1KMT2AALDH1A1GAA
SCHEMBL7570382 0.86 TSHR (0.75) TSHRMEN1KMT2AGRM4KDM4E
SCHEMBL3791578 0.85 TSHR (0.74) TSHRMEN1KMT2AGRM4KDM4E
SCHEMBL30557370 0.83 TSHR (0.71) TSHRMEN1KMT2APKMALDH1A1
SCHEMBL1970942 0.83 KMT2A (0.71) TSHRMEN1KMT2AGRM4KDM4E
SCHEMBL7592222 0.83 TSHR (0.71) TSHRMEN1KMT2APKMALDH1A1
SCHEMBL7085112 0.82 GAA (0.75) MEN1KMT2APKMERBB2HSP90AA1
SCHEMBL12197799 0.81 TSHR (0.63) TSHRMEN1KMT2AGRM4KDM4E
SCHEMBL7170804 0.80 ERBB2 (0.63) TSHRMEN1KMT2AKDM4EPTK2B
SCHEMBL1592863 0.79 ALDH1A1 (0.71) TSHRMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8349766-B2 Thermosensitive recording material FUJIFILM CORPORATION (JP) 2013-01-08 US disclosed
US-8039419-B2 Recording layer on support; hollow particles and coloring material FUJIFILM CORPORATION (JP) 2011-10-18 US disclosed
US-20110092365-A1 THERMOSENSITIVE RECORDING MATERIAL FUJIFILM CORPORATION (JP) 2011-04-21 US disclosed
US-20100048395-A1 THERMOSENSITIVE RECORDING MATERIAL FUJIFILM CORPORATION (JP) 2010-02-25 US disclosed
US-20080058207-A1 Recording layer on support; hollow particles and coloring material FUJIFILM CORPORATION (JP) 2008-03-06 US disclosed
US-7192904-B2 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-20 US disclosed
EP-1466753-B1 THERMAL RECORDING MATERIAL FUJI PHOTO FILM CO LTD (JP) 2007-02-14 EP disclosed
US-7098168-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2006-08-29 US disclosed
US-20060046933-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2006-03-02 US disclosed
US-20050170959-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2005-08-04 US disclosed
US-20050088508-A1 Heat-sensitive recording material FUJIFILM CORPORATION (JP) 2005-04-28 US disclosed
US-20050054527-A1 Thermal recording material FUJIFILM CORPORATION (JP) 2005-03-10 US disclosed
US-6852671-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2005-02-08 US disclosed
EP-1466751-A1 HEAT-SENSITIVE RECORDING MATERIAL Fuji Photo Film Co., Ltd. (JP) 2004-10-13 EP disclosed
EP-1466750-A1 HEAT-SENSITIVE RECORDING MATERIAL Fuji Photo Film Co., Ltd. (JP) 2004-10-13 EP disclosed
EP-1466752-A1 HEAT-SENSITIVE RECORDING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 2004-10-13 EP disclosed
EP-1466753-A1 THERMAL RECORDING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 2004-10-13 EP disclosed
US-20030148886-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2003-08-07 US disclosed
EP-1321306-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2003-06-25 EP disclosed
US-4585483-A Recording materials FUJI PHOTO FILM CO., LTD. (JP) 1986-04-29 US disclosed