SCHEMBL7592222

SCHEMBL7592222

Cc1ccc(S(=O)(=O)Nc2ccccc2Cl)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.71
MEN1 O00255 1/20 0.71
KMT2A Q03164 1/20 0.71
LMNA P02545 4/20 0.70
ALDH1A1 P00352 3/20 0.70
CYP2C9 P11712 2/20 0.70
CYP2C19 P33261 2/20 0.70
MAPT P10636 2/20 0.70
USP2 O75604 1/20 0.70
POLB P06746 1/20 0.70
NOD2 Q9HC29 1/20 0.70
L3MBTL1 Q9Y468 1/20 0.70
KEAP1 Q14145 1/20 0.65
NFE2L2 Q16236 1/20 0.65
CA2 P00918 3/20 0.64
CA9 Q16790 3/20 0.64
CA1 P00915 2/20 0.64
CA4 P22748 1/20 0.64
CA7 P43166 1/20 0.64
CA12 O43570 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30557370 1.00 TSHR (0.71) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL2068526 0.87 LMNA (0.82) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL2176669 0.87 LMNA (0.61) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL7570382 0.86 TSHR (0.75) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL3791578 0.85 TSHR (0.74) TSHRMEN1KMT2AALDH1A1KEAP1
SCHEMBL28605728 0.85 ALDH1A1 (0.59) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL31402302 0.84 KMT2A (0.59) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL11785265 0.84 LMNA (0.77) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL10337052 0.83 KMT2A (0.51) TSHRMEN1KMT2ALMNAALDH1A1
SCHEMBL1592846 0.83 TSHR (0.71) TSHRMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0104353-B1 HEAT SENSITIVE RECORD MATERIAL HODOGAYA CHEMICAL CO., LTD. (JP) 1987-10-28 EP claimed
US-4482905-A FLUORAN, BENZENESULFONAMIDE, ACID, BINDER HODOGAYA CHEMICAL CO., LTD. (JP) 1984-11-13 US claimed
EP-0104353-A2 Heat sensitive record material HODOGAYA CHEMICAL CO., LTD. (JP) 1984-04-04 EP claimed
US-12427798-B2 Heat-sensitive recording composition NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-09-30 US disclosed
US-20250001788-A1 HEAT-SENSITIVE RECORDING COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2025-01-02 US disclosed
EP-4442468-A1 HEAT-SENSITIVE RECORDING COMPOSITION Nippon Kayaku Kabushiki Kaisha (JP) 2024-10-09 EP disclosed
EP-4442467-A1 THERMAL RECORDING COMPOSITION Nippon Kayaku Kabushiki Kaisha (JP) 2024-10-09 EP disclosed
US-20240326501-A1 HEAT-SENSITIVE RECORDING COMPOSITION NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2024-10-03 US disclosed
WO-2023100902-A1 HEAT-SENSITIVE RECORDING COMPOSITION 日本化薬株式会社 2023-06-08 WO disclosed
WO-2023100900-A1 THERMAL RECORDING COMPOSITION 日本化薬株式会社 2023-06-08 WO disclosed
CN-112533967-A Oil-in-water emulsion of active energy ray-curable resin composition and thermal recording material 日本化药株式会社 2021-03-19 CN disclosed
WO-1998021178-A1 N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS DOW AGROSCIENCES LLC (US) 1998-05-22 WO disclosed
US-5399455-A Electrophotographic toner composition and image fixing process FUJI XEROX CO., LTD. (JP) 1995-03-21 US disclosed
US-4929530-A OXIDATIVE LEUCO DYES, PHOTO-OXIDIZERS, REDUCING AGENTS, ORGANIC SULFONAMIDES AND PHENOLIC COMPONENTS; EXPOSING TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1990-05-29 US disclosed
US-4824721-A CAPSULES OF OIL SOLUBLE DYES WHICH SWELL AND RELEASE DYE UPON HEATING FUJI PHOTO FILM CO., LTD. (JP) 1989-04-25 US disclosed
US-4758495-A Diazo microcapsule recording material prepared using ion exchange treatment FUJI PHOTO FILM CO., LTD. (JP) 1988-07-19 US disclosed
US-4749679-A Heat sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1988-06-07 US disclosed
EP-0262953-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-04-06 EP disclosed
US-4682194-A MICROCAPSULES CONTAINING LEUCO DYE FUJI PHOTO FILM CO., LTD. (JP) 1987-07-21 US disclosed
US-4644376-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-02-17 US disclosed