Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4B | O94953 | 2/20 | 0.58 |
| ▸ | KDM5C | P41229 | 2/20 | 0.58 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.56 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.47 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946431 | 0.86 | ASIC3 (0.55) | KDM4BKDM5CKDM5BMAP4K4PIM1 | |
| SCHEMBL7038517 | 0.85 | KDM5C (0.69) | KDM4BKDM5CKDM5BMAP4K4PIM1 | |
| SCHEMBL28907344 | 0.84 | KDM4B (0.56) | KDM4BKDM5CKDM5BMAP4K4PIM1 | |
| SCHEMBL29932888 | 0.84 | MAP4K4 (0.55) | KDM4BKDM5CKDM5BMAP4K4PIM1 | |
| SCHEMBL1759899 | 0.84 | KMO (0.61) | KDM4BKDM5CKDM5BKMOLOXL2 | |
| SCHEMBL28856057 | 0.83 | MAP4K4 (0.54) | KDM4BKDM5CKDM5BMAP4K4PIM1 | |
| SCHEMBL31582735 | 0.83 | KDM5C (0.55) | KDM4BKDM5CKDM5BMAP4K4PIM1 | |
| SCHEMBL1758188 | 0.83 | MAP4K4 (0.57) | KDM4BKDM5CKDM5BMAP4K4PIM1 | |
| SCHEMBL29932995 | 0.83 | MAP4K4 (0.54) | KDM4BKDM5CKDM5BMAP4K4PIM1 | |
| SCHEMBL3718581 | 0.82 | HDAC1 (0.56) | KDM4BKDM5CKDM5BMAP4K4CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150361102-A1 | METHOD FOR PRODUCING METAL COMPLEX | KURARAY CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |
| US-20110092505-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092505-A1 | ORGANIC COMPOUNDS | SLCO2B1, SLCO1B1, SLCO1B3 | KDM4B 2668/4885KDM5C 2504/4885KDM5B 2644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.