Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15928835 | 0.94 | PTGS2 (0.48) | PTGS2TRAP1HDAC3HDAC4HDAC1 | |
| SCHEMBL15928943 | 0.91 | TRAP1 (0.54) | PTGS2TRAP1HDAC3HDAC4HDAC1 | |
| SCHEMBL15928871 | 0.91 | PTGS2 (0.56) | PTGS2TRAP1HDAC3HDAC4HDAC1 | |
| SCHEMBL14697027 | 0.90 | TRAP1 (0.52) | PTGS2TRAP1HDAC3HDAC4HDAC1 | |
| SCHEMBL15928865 | 0.90 | PTGS2 (0.53) | PTGS2TRAP1HDAC3HDAC4HDAC1 | |
| SCHEMBL19341433 | 0.88 | TRAP1 (0.45) | PTGS2TRAP1HDAC3HDAC4HDAC1 | |
| SCHEMBL15928942 | 0.88 | PTGS2 (0.51) | PTGS2TRAP1HDAC3HDAC4HDAC1 | |
| SCHEMBL15928870 | 0.87 | TRAP1 (0.47) | PTGS2TRAP1HDAC3HDAC4HDAC1 | |
| SCHEMBL19341431 | 0.86 | PTGS2 (0.48) | PTGS2TRAP1HDAC3HDAC4HDAC1 | |
| SCHEMBL15928890 | 0.86 | TRAP1 (0.46) | PTGS2TRAP1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450260-B2 | NO- and H2S-releasing compounds | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2019-10-22 | — | — | US | disclosed |
| US-20170260124-A1 | NO- AND H2S- RELEASING COMPOUNDS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK | 2017-09-14 | — | — | US | disclosed |
| US-9688607-B2 | No- and H2S-releasing compounds | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2017-06-27 | — | — | US | disclosed |
| US-20170174651-A1 | Method of Priming Plants Against Abiotic Stress Factors | CYPRUS UNIVERSITY OF TECHNOLOGY (CY) | 2017-06-22 | — | — | US | disclosed |
| US-20140221316-A1 | NO- AND H2S- RELEASING COMPOUNDS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221316-A1 | NO- AND H2S- RELEASING COMPOUNDS | PTGS1, NOS2, NOS1 | PTGS2 4/4885TRAP1 639/4885HDAC3 1591/4885 |
| US-20170260124-A1 | NO- AND H2S- RELEASING COMPOUNDS | NOS2, NOS3, NOS1 | PTGS2 9/4885TRAP1 720/4885HDAC3 1246/4885 |
| US-10450260-B2 | NO- and H2S-releasing compounds | NOS2, NOS3, NOS1 | PTGS2 9/4885TRAP1 720/4885HDAC3 1246/4885 |
| US-20170174651-A1 | Method of Priming Plants Against Abiotic Stress Factors | NOS2, NOS1, HSF1 | PTGS2 6/4885TRAP1 77/4885HDAC3 3014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.