Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 14/20 | 0.48 |
| ▸ | FAAH | O00519 | 5/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15928046 | 0.94 | MGLL (0.47) | MGLLFAAHHSP90AA1TDP1NPSR1 | |
| SCHEMBL15929435 | 0.90 | MGLL (0.45) | MGLLFAAHHSP90AA1TDP1NPSR1 | |
| SCHEMBL15928048 | 0.88 | MGLL (0.42) | MGLLFAAHHSP90AA1TDP1NPSR1 | |
| SCHEMBL22479280 | 0.77 | MEN1 (0.38) | TDP1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL22236844 | 0.75 | CA12 (0.35) | ALDH1A1HPGDHTTLMNAMAPT | |
| SCHEMBL15929419 | 0.74 | MAPT (0.41) | TDP1ALDH1A1LMNAMAPT | |
| SCHEMBL18133295 | 0.74 | MGLL (0.39) | MGLLFAAHHSP90AA1TDP1NPSR1 | |
| SCHEMBL15929407 | 0.74 | LMNA (0.35) | ALDH1A1LMNAMAPTRECQL | |
| SCHEMBL15929413 | 0.71 | HDAC6 (0.34) | ALDH1A1HPGDHTTLMNARECQL | |
| SCHEMBL15929412 | 0.71 | DNM1 (0.32) | ALDH1A1LMNAMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542267-B2 | Cryptate compounds | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2023-01-03 | — | — | US | disclosed |
| US-11535623-B2 | Cryptate compounds | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2022-12-27 | — | — | US | disclosed |
| US-20200308183-A1 | CRYPTATE COMPOUNDS | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2020-10-01 | — | — | US | disclosed |
| US-20200308182-A1 | CRYPTATE COMPOUNDS | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2020-10-01 | — | — | US | disclosed |
| US-10717741-B2 | Cryptate compounds | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2020-07-21 | — | — | US | disclosed |
| US-20140219915-A1 | CRYPTATE COMPOUNDS | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308183-A1 | CRYPTATE COMPOUNDS | HCCS, SQOR, NQO1 | MGLL 4179/4885FAAH 3726/4885HSP90AA1 3157/4885 |
| US-20140219915-A1 | CRYPTATE COMPOUNDS | HCCS, SQOR, NQO1 | MGLL 4179/4885FAAH 3726/4885HSP90AA1 3157/4885 |
| US-11542267-B2 | Cryptate compounds | HCCS, SQOR, NQO1 | MGLL 4179/4885FAAH 3726/4885HSP90AA1 3157/4885 |
| US-20200308182-A1 | CRYPTATE COMPOUNDS | HCCS, SQOR, NQO1 | MGLL 4179/4885FAAH 3726/4885HSP90AA1 3157/4885 |
| US-10717741-B2 | Cryptate compounds | HCCS, SQOR, NQO1 | MGLL 4179/4885FAAH 3726/4885HSP90AA1 3157/4885 |
| US-11535623-B2 | Cryptate compounds | HCCS, SQOR, NQO1 | MGLL 4179/4885FAAH 3726/4885HSP90AA1 3157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.