Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15928049 | 0.94 | HDAC6 (0.36) | HDAC6LMNAHDAC8RAB9AHTT | |
| SCHEMBL15929457 | 0.92 | HDAC6 (0.34) | HDAC6LMNAHDAC8RAB9AHTT | |
| SCHEMBL15928056 | 0.89 | HDAC6 (0.33) | HDAC6LMNAHDAC8RAB9AHTT | |
| SCHEMBL22488653 | 0.79 | SMN1; SMN2 (0.31) | LMNARAB9AHTTNPC1HPGD | |
| SCHEMBL17071632 | 0.75 | ALDH1A1 (0.47) | LMNARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL3418246 | 0.74 | LOXL2 (0.49) | HDAC6LMNAHDAC8RAB9AHTT | |
| SCHEMBL17787294 | 0.73 | KMT2A (0.53) | HDAC6HDAC8RAB9AHTTKMT2A | |
| SCHEMBL26167885 | 0.72 | ADRB2 (0.41) | HDAC6LMNARAB9AHTTNPC1 | |
| SCHEMBL15929409 | 0.71 | MGLL (0.48) | LMNAHTTHPGDALDH1A1RECQL | |
| SCHEMBL22479280 | 0.71 | MEN1 (0.38) | LMNAKMT2AMEN1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542267-B2 | Cryptate compounds | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2023-01-03 | — | — | US | disclosed |
| US-20200308182-A1 | CRYPTATE COMPOUNDS | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2020-10-01 | — | — | US | disclosed |
| US-10717741-B2 | Cryptate compounds | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2020-07-21 | — | — | US | disclosed |
| US-20140219915-A1 | CRYPTATE COMPOUNDS | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140219915-A1 | CRYPTATE COMPOUNDS | HCCS, SQOR, NQO1 | HDAC6 613/4885LMNA 2573/4885HDAC8 618/4885 |
| US-11542267-B2 | Cryptate compounds | HCCS, SQOR, NQO1 | HDAC6 613/4885LMNA 2573/4885HDAC8 618/4885 |
| US-20200308182-A1 | CRYPTATE COMPOUNDS | HCCS, SQOR, NQO1 | HDAC6 613/4885LMNA 2573/4885HDAC8 618/4885 |
| US-10717741-B2 | Cryptate compounds | HCCS, SQOR, NQO1 | HDAC6 613/4885LMNA 2573/4885HDAC8 618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.