SCHEMBL703030

SCHEMBL703030

Nc1ccc(Cl)cc1CO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.52
ALOX15 P16050 4/20 0.52
SMN1; SMN2 Q16637 4/20 0.52
TSHR P16473 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
HPGD P15428 3/20 0.46
ALOX12 P18054 2/20 0.46
HSD17B10 Q99714 2/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 4/20 0.45
HIF1A Q16665 3/20 0.45
IDO1 P14902 3/20 0.45
MAPT P10636 2/20 0.45
MEN1 O00255 2/20 0.45
SLC22A1 O15245 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
HSP90AA1 P07900 1/20 0.45
HSPD1 P10809 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5107799 0.83 CYP3A4 (0.48) CYP3A4ALOX15SMN1; SMN2TSHRALDH1A1
SCHEMBL1373616 0.82 CYP3A4 (0.52) CYP3A4ALOX15SMN1; SMN2TSHRALDH1A1
SCHEMBL12533057 0.79 CYP3A4 (0.45) CYP3A4ALOX15SMN1; SMN2TSHRALDH1A1
SCHEMBL775188 0.79 CYP3A4 (0.54) CYP3A4ALOX15SMN1; SMN2TSHRALDH1A1
SCHEMBL1154758 0.78 IDO1 (0.50) CYP3A4ALOX15SMN1; SMN2TSHRALDH1A1
SCHEMBL29493203 0.78 IDO1 (0.50) CYP3A4ALOX15SMN1; SMN2TSHRALDH1A1
SCHEMBL775187 0.77 CYP3A4 (0.52) CYP3A4ALOX15SMN1; SMN2TSHRALDH1A1
SCHEMBL6055610 0.77 CYP3A4 (0.52) CYP3A4ALOX15SMN1; SMN2TSHRALDH1A1
SCHEMBL3786384 0.77 CYP3A4 (0.52) CYP3A4ALOX15SMN1; SMN2TSHRALDH1A1
SCHEMBL11737566 0.77 CYP3A4 (0.46) CYP3A4ALOX15SMN1; SMN2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119098205-A Nitrogen-doped porous carbon-loaded cobalt monoatomic catalyst and preparation method and application thereof 南京理工大学 2024-12-10 CN claimed
CN-109180661-A The chloro- 2-(thienyl -2- base of 6-) quinazoline synthetic method 郑州大学 2019-01-11 CN claimed
US-7547713-B2 O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives GU LIANQUAN 2009-06-16 US claimed
CN-1284773-C Ortho-pyridinequinone derivative, composite containing said derivative, its preparation method and application BAIRUI GLOBAL CO LTD (VG) 2006-11-15 CN claimed
US-20060111405-A1 O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives GU LIANQUAN 2006-05-25 US claimed
CN-1477099-A O-pyridinoquinone derivative, composition containing the same, preparation method and use of the same 百瑞全球有限公司 2004-02-25 CN claimed
US-6509393-B2 Phase change inks XEROX CORPORATION 2003-01-21 US claimed
US-20020137816-A1 Phase change inks XEROX CORPORATION 2002-09-26 US claimed
CN-121159410-A Preparation method of 2-amino-5-chlorobenzenemethanol 枣阳市福星化工有限公司 2025-12-19 CN disclosed
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2025-07-01 US disclosed
CN-116375641-B C3-phenoxy substituted quinoline compound and synthetic method and application thereof 杭州师范大学 2025-01-03 CN disclosed
CN-119098205-A Nitrogen-doped porous carbon-loaded cobalt monoatomic catalyst and preparation method and application thereof 南京理工大学 2024-12-10 CN disclosed
US-20240199612-A1 IMIDAZOPYRIDINYL INHIBITORS OF PLASMA KALLIKREIN SHIRE HUMAN GENETIC THERAPIES (US) 2024-06-20 US disclosed
EP-4308227-A1 IMIDAZOPYRIDINYL INHIBITORS OF PLASMA KALLIKREIN Takeda Pharmaceutical Company Limited (JP) 2024-01-24 EP disclosed
US-4268510-A DEMETHANIZATION, METABOLISM, RUMEN IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-05-19 US disclosed
US-4214889-A Benzoxazine herbicides SANDOZ, INC. (US) 1980-07-29 US disclosed
EP-0010348-A1 Heterocyclic trichloromethyl derivatives, process for their preparation and their use IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-04-30 EP disclosed
US-4164407-A Benzoxazine herbicides SANDOZ, INC. (US) 1979-08-14 US disclosed
US-4002621-A 6-Chloro-2-(3,4-dichloroanilino)-4H-3,1-benzothiazine MORTON-NORWICH PRODUCTS, INC. (US) 1977-01-11 US disclosed
US-4002620-A 2-Anilino-4H-3,1-benzothiazines MORTON-NORWICH PRODUCTS, INC. (US) 1977-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060111405-A1 O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives PTGS2, PTGES2, PTGES CYP3A4 32/4885ALOX15 227/4885SMN1; SMN2 3704/4885
US-20240199612-A1 IMIDAZOPYRIDINYL INHIBITORS OF PLASMA KALLIKREIN KLKB1, KLK1, KLK4 CYP3A4 975/4885ALOX15 4285/4885SMN1; SMN2 4781/4885
US-12344571-B1 Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture NOS1, NOS3, NOS2 CYP3A4 1460/4885ALOX15 1639/4885SMN1; SMN2 690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.