Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCK | P27707 | 2/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933578 | 0.84 | HRH3 (0.47) | DCKKDM4ERAB9AALDH1A1MEN1 | |
| SCHEMBL15933569 | 0.83 | RAB9A (0.48) | DCKPPARAKDM4ERAB9ALMNA | |
| SCHEMBL8989264 | 0.82 | TRPM8 (0.47) | DCKMPOPPARAKDM4EGAA | |
| SCHEMBL8989133 | 0.82 | MPO (0.43) | DCKMPOPPARAKDM4EGAA | |
| SCHEMBL14736584 | 0.79 | PPARA (0.46) | DCKMPOPPARAKDM4EGAA | |
| SCHEMBL820915 | 0.79 | PPARA (0.49) | DCKMPOPPARAKDM4EGAA | |
| SCHEMBL4462240 | 0.77 | KDM4E (0.57) | PPARAKDM4EGAARAB9AALDH1A1 | |
| SCHEMBL14736582 | 0.76 | ALDH1A1 (0.50) | MPOPPARAKDM4EGAARAB9A | |
| SCHEMBL4138997 | 0.75 | KDM4E (0.58) | KDM4EGAARAB9AALOX5ALDH1A1 | |
| SCHEMBL14736575 | 0.74 | PPARA (0.43) | DCKMPOPPARAKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014117318-A1 | NOVEL TRIAZOLE ANTIFUNGAL COMPOUNDS, AND PHARMACEUTICAL COMPOSITION, PREPARATION METHOD, AND APPLICATION THEREOF | 中国科学院上海药物研究所 (CN) | 2014-08-07 | — | — | WO | disclosed |