Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 2/20 | 0.40 |
| ▸ | SKP1 | P63208 | 2/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933677 | 0.85 | GPR119 (0.53) | CKS1BSKP1SKP2GPR119JAK2 | |
| SCHEMBL31612680 | 0.83 | HDAC4 (0.48) | HDAC4HDAC6GPR119DPP4DPP8 | |
| SCHEMBL17984905 | 0.83 | ESR2 (0.40) | HDAC4CKS1BSKP1SKP2HDAC6 | |
| SCHEMBL20140942 | 0.82 | CKS1B (0.49) | HDAC4CKS1BSKP1SKP2GPR119 | |
| SCHEMBL15933643 | 0.81 | GPR119 (0.45) | HDAC4CKS1BSKP1SKP2GPR119 | |
| SCHEMBL15933697 | 0.81 | GPR119 (0.47) | HDAC4CKS1BSKP1SKP2GPR119 | |
| SCHEMBL15933678 | 0.81 | CSNK1D (0.43) | HDAC4CKS1BSKP1SKP2GPR119 | |
| SCHEMBL24689567 | 0.80 | NR1H2 (0.43) | HDAC4GPR119DPP4DPP8DPP7 | |
| SCHEMBL15933535 | 0.80 | GPR119 (0.49) | HDAC4GPR119ESR2JAK2JAK1 | |
| SCHEMBL31612664 | 0.79 | MAPT (0.40) | HDAC4CKS1BSKP1SKP2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014117318-A1 | NOVEL TRIAZOLE ANTIFUNGAL COMPOUNDS, AND PHARMACEUTICAL COMPOSITION, PREPARATION METHOD, AND APPLICATION THEREOF | 中国科学院上海药物研究所 (CN) | 2014-08-07 | — | — | WO | disclosed |