SCHEMBL15933677 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	GPR119	Q8TDV5	10/20	0.53

▸	JAK2	O60674	1/20	0.40

▸	JAK1	P23458	1/20	0.40

▸	NR1H2	P55055	1/20	0.39

▸	NR1H3	Q13133	1/20	0.39

▸	RET	P07949	4/20	0.39

▸	CKS1B	P61024	1/20	0.38

▸	SKP1	P63208	1/20	0.38

▸	SKP2	Q13309	1/20	0.38

▸	BRD4	O60885	1/20	0.38

▸	CREBBP	Q92793	1/20	0.38

▸	EGLN2	Q96KS0	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15933535	0.86	GPR119 (0.49)	GPR119JAK2JAK1EGLN2
SCHEMBL15933477	0.85	HDAC4 (0.40)	GPR119JAK2JAK1NR1H2CKS1B
SCHEMBL15933586	0.81	GPR119 (0.52)	GPR119JAK2JAK1NR1H2NR1H3
SCHEMBL15933683	0.81	GPR119 (0.52)	GPR119BRD4CREBBPEGLN2
SCHEMBL20140942	0.80	CKS1B (0.49)	GPR119JAK2CKS1BSKP1SKP2
SCHEMBL24689592	0.79	PDE10A (0.42)	GPR119NR1H2
SCHEMBL15933643	0.79	GPR119 (0.45)	GPR119NR1H2CKS1BSKP1SKP2
SCHEMBL15933697	0.79	GPR119 (0.47)	GPR119NR1H2CKS1BSKP1SKP2
SCHEMBL31612680	0.79	HDAC4 (0.48)	GPR119
SCHEMBL24689567	0.78	NR1H2 (0.43)	GPR119NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2014117318-A1	NOVEL TRIAZOLE ANTIFUNGAL COMPOUNDS, AND PHARMACEUTICAL COMPOSITION, PREPARATION METHOD, AND APPLICATION THEREOF	中国科学院上海药物研究所 (CN)	2014-08-07	—	—	WO	disclosed