SCHEMBL1593490

SCHEMBL1593490

c1ccc2c(N(c3ccc(-c4ccc(N(c5ccc(-n6c7ccccc7c7ccccc76)cc5)c5cccc6ccccc56)cc4)cc3)c3ccc(-n4c5ccccc5c5ccccc54)cc3)cccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HDAC4 P56524 1/20 0.38
SIGMAR1 Q99720 6/20 0.35
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
PER2 O15055 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
CRY1 Q16526 1/20 0.34
CRY2 Q49AN0 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
F2 P00734 1/20 0.31
F10 P00742 1/20 0.31
PRSS1 P07477 1/20 0.31
PTPN1 P18031 2/20 0.31
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13620184 0.97 L3MBTL1 (0.46) KDM4EATML3MBTL1HDAC4SIGMAR1
SCHEMBL10029893 0.97 L3MBTL1 (0.46) KDM4EATML3MBTL1HDAC4SIGMAR1
SCHEMBL10029866 0.97 L3MBTL1 (0.46) KDM4EATML3MBTL1HDAC4SIGMAR1
SCHEMBL12704841 0.97 L3MBTL1 (0.46) KDM4EATML3MBTL1HDAC4SIGMAR1
SCHEMBL3732155 0.97 L3MBTL1 (0.46) KDM4EATML3MBTL1HDAC4SIGMAR1
SCHEMBL10029910 0.97 L3MBTL1 (0.46) KDM4EATML3MBTL1HDAC4SIGMAR1
SCHEMBL15138344 0.97 KDM4E (0.44) KDM4EATML3MBTL1HDAC4SIGMAR1
SCHEMBL4398150 0.96 KDM4E (0.41) KDM4EATML3MBTL1HDAC4SIGMAR1
SCHEMBL11887589 0.96 KDM4E (0.41) KDM4EATML3MBTL1HDAC4SIGMAR1
SCHEMBL16356550 0.96 L3MBTL1 (0.45) KDM4EATML3MBTL1HDAC4SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7919773-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic appliance using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-05 US disclosed
US-7919773-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic appliance using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-05 US disclosed
US-7919773-B2 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic appliance using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-04-05 US disclosed
US-20100001638-A1 AROMATIC AMINE COMPOUND, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPLIANCE USING THE AROMATIC AMINE COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-01-07 US disclosed
US-20100001638-A1 AROMATIC AMINE COMPOUND, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPLIANCE USING THE AROMATIC AMINE COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-01-07 US disclosed
US-20100001638-A1 AROMATIC AMINE COMPOUND, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPLIANCE USING THE AROMATIC AMINE COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-01-07 US disclosed
US-20090039765-A1 LIGHT EMITTING POLYMER COMPOSITION AND POLYMER LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-12 US disclosed
US-20090039765-A1 LIGHT EMITTING POLYMER COMPOSITION AND POLYMER LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-12 US disclosed
US-20070215889-A1 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic appliance using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-09-20 US disclosed
US-20070215889-A1 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic appliance using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-09-20 US disclosed
US-20070215889-A1 Aromatic amine compound, and light-emitting element, light-emitting device, and electronic appliance using the aromatic amine compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090039765-A1 LIGHT EMITTING POLYMER COMPOSITION AND POLYMER LIGHT EMITTING DEVICE CYBA, BCAT1, CRY1 KDM4E 613/4885ATM 1052/4885L3MBTL1 319/4885
US-20100001638-A1 AROMATIC AMINE COMPOUND, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPLIANCE USING THE AROMATIC AMINE COMPOUND DDC, ARNT, TYR KDM4E 243/4885ATM 797/4885L3MBTL1 1096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.