Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | BACE1 | P56817 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15940242 | 1.00 | CTSK (0.55) | CTSKBACE1MAOBLMNAMAPT | |
| SCHEMBL3748239 | 0.87 | PTPN1 (0.52) | MEN1ALDH1A1KMT2APTPN1CYP1A2 | |
| SCHEMBL6023355 | 0.86 | BACE1 (0.48) | CTSKBACE1MAOBLMNAMAPT | |
| SCHEMBL6027405 | 0.86 | BACE1 (0.48) | CTSKBACE1MAOBLMNAMAPT | |
| SCHEMBL28036 | 0.82 | MAPT (0.60) | BACE1MAOBLMNAMAPTPPARG | |
| SCHEMBL28035 | 0.82 | MAPT (0.60) | BACE1MAOBLMNAMAPTPPARG | |
| SCHEMBL5604693 | 0.82 | MAPT (0.60) | BACE1MAOBLMNAMAPTPPARG | |
| Geroquinol SCHEMBL29929565 | 0.81 | ALOX5 (0.57) | CTSKBACE1MAOBAPPPTPN1 | |
| Geroquinol SCHEMBL557012 | 0.81 | ALOX5 (0.57) | CTSKBACE1MAOBAPPPTPN1 | |
| Geroquinol SCHEMBL557013 | 0.81 | ALOX5 (0.57) | CTSKBACE1MAOBAPPPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108865961-B | Method for synthesizing 3-geranyl-4-hydroxybenzoic acid and xiamenmycin by using escherichia coli | 上海交通大学 | 2020-07-14 | — | — | CN | disclosed |
| US-10011839-B2 | Metabolic transistor in bacteria | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-07-03 | — | — | US | disclosed |
| US-20170009241-A1 | METABOLIC TRANSISTOR IN BACTERIA | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-01-12 | — | — | US | disclosed |
| US-9441253-B2 | Metabolic transistor in bacteria | WILLIAM MARSH RICE UNIVERSITY (US) | 2016-09-13 | — | — | US | disclosed |
| US-20140227745-A1 | METABOLIC TRANSISTOR IN BACTERIA | WILLIAM MARSH RICE UNIVERSITY (US) | 2014-08-14 | — | — | US | disclosed |