Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18897831 | 0.83 | KDM4E (0.43) | CYP1A2CYP3A4CYP2D6KMT2AKDR | |
| SCHEMBL13131268 | 0.78 | KDM4E (0.48) | KMT2AALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL2818115 | 0.78 | TYMS (0.58) | KMT2AALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL2817520 | 0.78 | ADORA2A (0.52) | CYP1A2CYP3A4CYP2D6KMT2ADYRK1A | |
| SCHEMBL2816677 | 0.75 | HTR2C (0.51) | KMT2ALCKALDH1A1KDM4EMEN1 | |
| SCHEMBL2817449 | 0.75 | IKBKB (0.50) | CYP1A2KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL16482324 | 0.73 | POLB (0.42) | KMT2AKDRLCKFYNGSK3B | |
| SCHEMBL5401331 | 0.72 | IKBKB (0.45) | CYP1A2CYP3A4CYP2D6LCKFLT3 | |
| SCHEMBL5401324 | 0.72 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2D6KMT2AKDR | |
| SCHEMBL20876001 | 0.71 | RAB9A (0.56) | CYP1A2CYP3A4CYP2D6KDRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9802980-B2 | Method for producing pyrazoles, novel pyrazoles and applications thereof | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-10-31 | — | — | US | disclosed |
| US-9802980-B2 | Method for producing pyrazoles, novel pyrazoles and applications thereof | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-10-31 | — | — | US | disclosed |
| US-9802980-B2 | Method for producing pyrazoles, novel pyrazoles and applications thereof | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-10-31 | — | — | US | disclosed |
| US-20150368295-A1 | METHOD FOR PRODUCING PYRAZOLES, NOVEL PYRAZOLES AND APPLICATIONS THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-12-24 | — | — | US | disclosed |
| US-20150368295-A1 | METHOD FOR PRODUCING PYRAZOLES, NOVEL PYRAZOLES AND APPLICATIONS THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-12-24 | — | — | US | disclosed |
| US-20150368295-A1 | METHOD FOR PRODUCING PYRAZOLES, NOVEL PYRAZOLES AND APPLICATIONS THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2015-12-24 | — | — | US | disclosed |
| EP-2953935-A2 | METHOD FOR PRODUCING PYRAZOLES, NOVEL PYRAZOLES AND APPLICATIONS THEREOF | Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) | 2015-12-16 | — | — | EP | disclosed |
| WO-2014122407-A2 | METHOD FOR PRODUCING PYRAZOLES, NOVEL PYRAZOLES AND APPLICATIONS THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2014-08-14 | — | — | WO | disclosed |
| WO-2014122407-A2 | METHOD FOR PRODUCING PYRAZOLES, NOVEL PYRAZOLES AND APPLICATIONS THEREOF | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2014-08-14 | — | — | WO | disclosed |
| US-7745665-B2 | Substituted phenethylamines | AUSPEX PHARMACEUTICALS, INC. (US) | 2010-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368295-A1 | METHOD FOR PRODUCING PYRAZOLES, NOVEL PYRAZOLES AND APPLICATIONS THEREOF | NDUFS7, NDUFS3, UQCRB | CYP1A2 28/4885CYP3A4 220/4885CYP2D6 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.