Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15940757 | 0.88 | NPC1 (0.44) | NPC1RAB9AHTTMAPK10MAPK8 | |
| SCHEMBL22809622 | 0.85 | RAB9A (0.45) | NPC1RAB9AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL18266478 | 0.81 | JAK2 (0.50) | NPC1RAB9AHTTMAPK10ALDH1A1 | |
| SCHEMBL15910524 | 0.81 | L3MBTL1 (0.56) | NPC1RAB9AHTTMAPK10MAPK8 | |
| SCHEMBL15941191 | 0.81 | HPGD (0.56) | NPC1RAB9AHTTMAPK10MAPK8 | |
| SCHEMBL14784275 | 0.81 | TSHR (0.47) | NPC1RAB9AHTTALDH1A1L3MBTL1 | |
| SCHEMBL15940876 | 0.80 | NPC1 (0.45) | NPC1RAB9AHTTMAPK10MAPK8 | |
| SCHEMBL15910526 | 0.78 | HTT (0.47) | NPC1RAB9AHTTMAPK10MAPK8 | |
| SCHEMBL7365972 | 0.76 | L3MBTL1 (0.52) | L3MBTL1 | |
| SCHEMBL29951814 | 0.76 | L3MBTL1 (0.52) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014122065-A1 | 2-AMINOPYRIDINE DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |