SCHEMBL15945890

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15893284	0.95	ALOX5 (0.51)	ALOX5ESR1ESR2HSD17B1HSD17B2
	SCHEMBL17944371	0.90	ALOX5 (0.44)	ALOX5ESR1ESR2HSD17B1HSD17B2
	SCHEMBL15893285	0.90	ALOX5 (0.46)	ALOX5HSD17B1HSD17B2S1PR5S1PR4
	SCHEMBL17167469	0.90	ALOX5 (0.46)	ALOX5HSD17B1HSD17B2S1PR5S1PR4
	SCHEMBL23449000	0.89	ALOX5 (0.40)	ALOX5ESR1ESR2HSD17B1HSD17B2
	SCHEMBL21190410	0.87	ALOX5 (0.44)	ALOX5S1PR5S1PR4GSTP1
	SCHEMBL17944381	0.86	ALOX5 (0.46)	ALOX5HSD17B1HSD17B2S1PR5S1PR4
	SCHEMBL17931900	0.86	ALOX5 (0.42)	ALOX5HSD17B1HSD17B2S1PR5S1PR4
	SCHEMBL21190438	0.85	ALOX5 (0.43)	ALOX5S1PR5S1PR4
	SCHEMBL12996532	0.85	ALOX5 (0.43)	ALOX5ESR1ESR2HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.