SCHEMBL15893284

SCHEMBL15893284

c1ccc2cc(-c3ccc4cc(-c5cccc6c5sc5cc7ccccc7cc56)ccc4c3)ccc2c1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.51
GSTP1 P09211 1/20 0.42
S1PR5 Q9H228 14/20 0.41
S1PR4 O95977 12/20 0.41
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15945890 0.95 ALOX5 (0.47) ALOX5GSTP1S1PR5S1PR4HSD17B1
SCHEMBL17944381 0.90 ALOX5 (0.46) ALOX5GSTP1S1PR5S1PR4HSD17B1
SCHEMBL17167404 0.89 ALOX5 (0.64) ALOX5GSTP1S1PR5S1PR4HSD17B1
SCHEMBL10018879 0.89 ALOX5 (0.50) ALOX5GSTP1S1PR5S1PR4HSD17B1
SCHEMBL17944371 0.89 ALOX5 (0.44) ALOX5GSTP1S1PR5S1PR4HSD17B1
SCHEMBL22706347 0.89 ALOX5 (0.44) ALOX5GSTP1S1PR5S1PR4HSD17B1
SCHEMBL21190410 0.88 ALOX5 (0.44) ALOX5GSTP1S1PR5S1PR4
SCHEMBL15893274 0.88 ALOX5 (0.51) ALOX5GSTP1S1PR5S1PR4
SCHEMBL18086206 0.88 ALOX5 (0.66) ALOX5GSTP1S1PR5S1PR4HDAC4
SCHEMBL23449000 0.88 ALOX5 (0.40) ALOX5GSTP1S1PR5S1PR4HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-10038152-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-07-31 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
US-9899613-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2018-02-20 US disclosed
EP-2939289-B1 ORGANIC LIGHT-EMITTING ELEMENT CANON KK (JP) 2017-07-26 EP disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150357586-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed
US-20150295188-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-15 US disclosed
WO-2014123238-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2014-08-14 WO disclosed
WO-2014112658-A1 ORGANIC LIGHT-EMITTING ELEMENT CANON KABUSHIKI KAISHA (JP) 2014-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10038152-B2 Organic light-emitting element NFE2L2, EML4, LEF1 ALOX5 1144/4885GSTP1 1924/4885S1PR5 4848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.