Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15946181 | 0.93 | NLRP3 (0.37) | NLRP3HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL15940311 | 0.90 | NLRP3 (0.40) | NLRP3HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL15946178 | 0.88 | RAB9A (0.46) | NLRP3ALDH1A1GAAL3MBTL1 | |
| SCHEMBL15940161 | 0.81 | RAB9A (0.40) | HDAC1HDAC8HDAC6ESR1ESR2 | |
| SCHEMBL13299528 | 0.80 | NLRP3 (0.52) | NLRP3SIRT2SIRT1ESR1ESR2 | |
| SCHEMBL15940200 | 0.80 | ALDH1A1 (0.43) | NLRP3HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL15940224 | 0.78 | NLRP3 (0.47) | NLRP3HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL2456887 | 0.76 | ESR1 (0.51) | ESR1ESR2ALDH1A1PTGS2GAA | |
| SCHEMBL22522519 | 0.73 | ESR1 (0.46) | ESR1ESR2ALDH1A1PTGS2GAA | |
| SCHEMBL22507395 | 0.73 | ESR1 (0.46) | ESR1ESR2ALDH1A1PTGS2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140225069-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2014-08-14 | — | — | US | disclosed |